Neurostimulation is a mainstream treatment option for major depression. Neuromodulation
techniques apply repetitive magnetic or electrical stimulation to some neural target but …

Background A substantial number of patients with major depressive disorder (MDD) do not
sufficiently remit after the first lines of antidepressant treatments, making them vulnerable to …

To understand how cognitive dysfunction contributes to social cognitive deficits in
depression, we investigated the relationship between executive function and social cognitive …

Background Major depressive disorder is a complex heterogeneous disorder. Treatment is
especially challenging for patients with “difficult-to-treat depression” (DTD): a less …

BackgroundMagnetic resonance imaging (MRI) studies on major depressive disorder (MDD)
have predominantly found short-term electroconvulsive therapy (ECT)-related gray matter …

Methods Data collection was performed retrospectively by a chart review, including patient
files and medical records. A total of 64 patients (female= 60.9%) treated with ECT within the …

Introduction VNS is a non-pharmalogical neuromodulatory treatment option for difficult-to-treat
depression. A pulse generator implanted in the left chest area is connected to an …

Background: Obesity is a frequent somatic comorbidity of major depression, and it has been
associated with worse clinical outcomes and brain structural abnormalities. Converging …

Vagus nerve stimulation (VNS) represents a long-term adjunctive treatment option in patients
with difficult-to-treat depression (DTD). Anti-inflammatory effects have been discussed as a …

Einführung Seit 20 Jahren ist die Vagusnervstimulation (VNS) eine europaweit zugelassene
invasive Therapieoption für therapieresistente Depressionen (TRD). Im Gegensatz zu …