Identifying genetic variants influencing human brain structures may reveal new biological
mechanisms underlying cognition and neuropsychiatric illness. The volume of the …

OBJECTIVE: Previous work suggests that patients with unipolar depression may have
structural as well as functional abnormalities in limbic-thalamic-cortical networks, which are …

Context Identification of individuals at high risk of developing psychosis has relied on prodromal
symptomatology. Recently, machine learning algorithms have been successfully used …

The highly complex structure of the human brain is strongly shaped by genetic influences 1 .
Subcortical brain regions form circuits with cortical areas to coordinate movement 2 , …

Context Results of experimental studies suggest that neuroplastic changes may occur during
depressive episodes. These effects have not been confirmed in patients with depression, to …

Context Brain-derived neurotrophic factor (BDNF) modulates hippocampal plasticity, which
is believed to be altered in patients with major depression. Objective To examine the effect of …

Structural brain abnormalities are central to schizophrenia (SZ), but it remains unknown
whether they are linked to dysmaturational processes crossing diagnostic boundaries, …

Background: The amygdala plays a crucial role in the mediation of affective behavior in humans
and is implemented in the limbic-thalamic-cortical network that is supposed to modulate …

Early emotional stress is associated with a life-long burden of risk for later depression and
stressful life events contribute to the development of depressive episodes. In this study we …

Growing evidence from animal studies indicates brain‐damaging properties of nicotine
exposure. Investigations in humans found a wide range of functional cerebral effects of nicotine …