User profiles for Fangling Xuan

Fangling Xuan

Phd, University of Tartu
Verified email at ut.ee
Cited by 140

[HTML][HTML] CSF1R regulates schizophrenia-related stress response and vascular association of microglia/macrophages

L Yan, Y Li, F Fan, M Gou, F Xuan, W Feng… - BMC medicine, 2023 - Springer
Background Microglia are known to regulate stress and anxiety in both humans and animal
models. Psychosocial stress is the most common risk factor for the development of …

Comparative analysis of the rats' gut microbiota composition in animals with different ginsenosides metabolizing activity

WW Dong, FL Xuan, FL Zhong, J Jiang… - Journal of agricultural …, 2017 - ACS Publications
Following oral intake of Panax ginseng, major ginsenosides are metabolized to deglycosylated
ginsenosides by gut microbiota before absorption into the blood. As the composition of …

[HTML][HTML] Differences of microglia in the brain and the spinal cord

FL Xuan, K Chithanathan, K Lilleväli… - Frontiers in cellular …, 2019 - frontiersin.org
Microglia were previously regarded as a homogenous myeloid cell lineage in the mammalian
central nervous system (CNS). However, accumulating evidences show that microglia in …

[HTML][HTML] Glial receptor PLXNB2 regulates schizophrenia-related stress perception via the amygdala

FL Xuan, L Yan, Y Li, F Fan, H Deng, M Gou… - Frontiers in …, 2022 - frontiersin.org
Stress is a trigger for the development of psychiatric disorders. However, how stress trait
differs in schizophrenia patients is still unclear. Stress also induces and exacerbates immune …

[HTML][HTML] Enhanced anxiety and olfactory microglial activation in early-stage familial alzheimer's disease mouse model

K Chithanathan, FL Xuan, MA Hickey, L Tian - Biology, 2022 - mdpi.com
Simple Summary We observed that compared to wildtype (WT) littermates, 5 × FAD mice
showed enhanced anxiety with concomitant increased pro-inflammatory cytokines in the …

[HTML][HTML] Monocytic subsets impact cerebral cortex and cognition: differences between healthy subjects and patients with first-episode schizophrenia

S Chen, F Fan, FL Xuan, L Yan, M Xiu, H Fan… - Frontiers in …, 2022 - frontiersin.org
Monocytes are a highly heterogeneous population subcategorized into classical, intermediate
and nonclassical subsets. How monocytes and their subsets may shape brain structures …

TGF-β1 is associated with deficits in cognition and cerebral cortical thickness in first-episode schizophrenia

S Pan, Y Zhou, L Yan, F Xuan, J Tong, Y Li… - Journal of Psychiatry and …, 2022 - jpn.ca
Background: Evidence indicates that cytokines are associated with cognitive deficits in
schizophrenia; however, the underlying brain–behaviour mechanisms remain unclear. We …

[HTML][HTML] Propofol Inhibits Cerebellar Parallel Fiber-Purkinje Cell Synaptic Transmission via Activation of Presynaptic GABAB Receptors in vitro in Mice

FL Xuan, HW Wang, LX Cao, YH Bing… - Frontiers in …, 2018 - frontiersin.org
Propofol is a widely used intravenous sedative-hypnotic agent, which causes rapid and
reliable loss of consciousness via activation of γ -aminobutyric acid A (GABA A ) receptors. We …

[HTML][HTML] Replenished microglia partially rescue schizophrenia-related stress response

L Yan, FL Xuan, S Chen, M Gou, W Chen… - Frontiers in Cellular …, 2023 - ncbi.nlm.nih.gov
Background Microglia play an important role in the maintenance of brain and behavioral
homeostasis. The protective effect of microglial replenishment was reported in neurological …

Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human

…, F Cheng, CM Pan, H Xuan… - Proceedings of the …, 2005 - National Acad Sciences
The genomic sequences of severe acute respiratory syndrome coronaviruses from human
and palm civet of the 2003/2004 outbreak in the city of Guangzhou, China, were nearly …