User profiles for Fiona D. Zeeb
 | Fiona ZeebCentre for Addiction and Mental Health (CAMH); University of Toronto Verified email at camh.ca Cited by 2211 |
[HTML][HTML] Serotonergic and dopaminergic modulation of gambling behavior as assessed using a novel rat gambling task
Pathological gambling (PG) is characterized by persistent, maladaptive gambling behavior,
which disrupts personal and professional life. Animal models of gambling behavior could …
which disrupts personal and professional life. Animal models of gambling behavior could …
Contributions of the orbitofrontal cortex to impulsive choice: interactions with basal levels of impulsivity, dopamine signalling, and reward-related cues
Rationale Individual differences in impulsive decision-making may be critical determinants
of vulnerability to impulse control disorders and substance abuse, yet little is known of their …
of vulnerability to impulse control disorders and substance abuse, yet little is known of their …
Lesions of the basolateral amygdala and orbitofrontal cortex differentially affect acquisition and performance of a rodent gambling task
FD Zeeb, CA Winstanley - Journal of Neuroscience, 2011 - Soc Neuroscience
Risky decision making on the Iowa Gambling Task (IGT) has been observed in several
psychiatric disorders, including substance abuse, schizophrenia, and pathological gambling. …
psychiatric disorders, including substance abuse, schizophrenia, and pathological gambling. …
[HTML][HTML] Rodent versions of the iowa gambling task: opportunities and challenges for the understanding of decision-making
…, JR Homberg, M Mitsogiannis, FD Zeeb… - Frontiers in …, 2011 - frontiersin.org
Impaired decision-making is a core problem in several psychiatric disorders including
attention-deficit/hyperactivity disorder, schizophrenia, obsessive–compulsive disorder, mania, …
attention-deficit/hyperactivity disorder, schizophrenia, obsessive–compulsive disorder, mania, …
Functional disconnection of the orbitofrontal cortex and basolateral amygdala impairs acquisition of a rat gambling task and disrupts animals' ability to alter decision …
FD Zeeb, CA Winstanley - Journal of Neuroscience, 2013 - Soc Neuroscience
An inability to adjust choice preferences in response to changes in reward value may underlie
key symptoms of many psychiatric disorders, including chemical and behavioral addictions…
key symptoms of many psychiatric disorders, including chemical and behavioral addictions…
Differential effects of environmental enrichment, social-housing, and isolation-rearing on a rat gambling task: dissociations between impulsive action and risky …
FD Zeeb, AC Wong, CA Winstanley - Psychopharmacology, 2013 - Springer
Rationale Decision-making deficits, measured using the Iowa Gambling Task (IGT), are
observed in many psychiatric populations. Additionally, evidence suggests that the environment …
observed in many psychiatric populations. Additionally, evidence suggests that the environment …
Dopaminergic modulation of the orbitofrontal cortex affects attention, motivation and impulsive responding in rats performing the five-choice serial reaction time task
CA Winstanley, FD Zeeb, A Bedard, K Fu, B Lai… - Behavioural brain …, 2010 - Elsevier
Understanding the neurobiological factors underlying individual differences in impulsivity
may provide valuable insight into vulnerability to impulse control disorders. Recent data …
may provide valuable insight into vulnerability to impulse control disorders. Recent data …
Chronic atomoxetine treatment during adolescence decreases impulsive choice, but not impulsive action, in adult rats and alters markers of synaptic plasticity in the …
Rationale Impulsivity is a key symptom of attention-deficit hyperactivity disorder (ADHD). The
use of the norepinephrine reuptake inhibitor, atomoxetine, to treat ADHD suggests that the …
use of the norepinephrine reuptake inhibitor, atomoxetine, to treat ADHD suggests that the …
Inactivation of the prelimbic or infralimbic cortex impairs decision-making in the rat gambling task
FD Zeeb, PJJ Baarendse, L Vanderschuren… - …, 2015 - Springer
Rationale Studies employing the Iowa Gambling Task (IGT) demonstrated that areas of the
frontal cortex, including the ventromedial prefrontal cortex, orbitofrontal cortex (OFC), …
frontal cortex, including the ventromedial prefrontal cortex, orbitofrontal cortex (OFC), …
Yohimbine increases impulsivity through activation of cAMP response element binding in the orbitofrontal cortex
BACKGROUND: Stress can increase impulsivity and has a negative impact on psychiatric
outcome. Norepinephrine is heavily implicated in responses to stress, and the α 2 antagonist …
outcome. Norepinephrine is heavily implicated in responses to stress, and the α 2 antagonist …