Transposable elements (TEs) are mobile genetic sequences that can jump around the genome
from one location to another, behaving as genomic parasites. TEs have been particularly …

Neurogenesis in the dentate gyrus continues into adulthood, yet little is known about the
function of newly born neurons or how they integrate into an existing network of mature neurons…

Obesity is a chronic metabolic disorder affecting half a billion people worldwide. Major
difficulties in managing obesity are the cessation of continued weight loss in patients after an …

Cell-specific expression of many genes is conveyed by multiple enhancers, with each
individual enhancer controlling a particular expression domain. In contrast, multiple enhancers …

Deciphering the genetic bases that drive animal diversity is one of the major challenges of
modern biology. Although four decades ago it was proposed that animal evolution was mainly …

The proopiomelanocortin (POMC) gene is expressed in the pituitary and arcuate neurons of
the hypothalamus. POMC arcuate neurons play a central role in the control of energy …

The gene encoding the prohormone proopiomelanocortin (POMC) is mainly expressed in two
regions in vertebrates, namely corticotrophs and melanotrophs in the pituitary and a small …

Food intake and body weight regulation depend on proper expression of the proopiomelanocortin
gene (Pomc) in a group of neurons located in the mediobasal hypothalamus of all …

The anterior endomesoderm of the early Xenopus gastrula is a part of Spemann's organizer
and is important for head induction. Here we describe Xblimp1, which encodes a zinc finger …

The hypothalamus is a region of the anterior forebrain that controls basic aspects of vertebrate
physiology, but the genes involved in its development are still poorly understood. Here, …