User profiles for François Charih

François Charih

Carleton University
Verified email at sce.carleton.ca
Cited by 153

Unraveling the battle for lysine: A review of the competition among post-translational modifications

AH Shukri, V Lukinović, F Charih, KK Biggar - Biochimica et Biophysica …, 2023 - Elsevier
Proteins play a critical role as key regulators in various biological systems, influencing
crucial processes such as gene expression, cell cycle progression, and cellular proliferation. …

[PDF][PDF] Sex differences in developmental patterns of neocortical astroglia: A mouse translatome database

…, S Simard, M Freitas-Andrade, B Lacoste, F Charih… - Cell reports, 2022 - cell.com
Astroglial cells are key players in the development and maintenance of neurons and neuronal
networks. Astroglia express steroid hormone receptors and show rapid responses to …

[HTML][HTML] Data-driven audiogram classification for mobile audiometry

F Charih, M Bromwich, AE Mark, R Lefrançois… - Scientific Reports, 2020 - nature.com
Recent mobile and automated audiometry technologies have allowed for the democratization
of hearing healthcare and enables non-experts to deliver hearing tests. The problem …

[HTML][HTML] Functional insights into the interplay between DNA interaction and metal coordination in ferric uptake regulators

S Sarvan, F Charih, M Askoura, J Butcher… - Scientific reports, 2018 - nature.com
Ferric uptake regulators (Fur) are a family of transcription factors coupling gene regulatory
events to metal concentration. Recent evidence has expanded the mechanistic repertoires …

[PDF][PDF] Proteome-wide prediction of lysine methylation leads to identification of H2BK43 methylation and outlines the potential methyllysine proteome

KK Biggar, F Charih, H Liu, YB Ruiz-Blanco, L Stalker… - Cell Reports, 2020 - cell.com
Protein Lys methylation plays a critical role in numerous cellular processes, but it is
challenging to identify Lys methylation in a systematic manner. Here we present an approach …

[HTML][HTML] Assessing sequence-based protein–protein interaction predictors for use in therapeutic peptide engineering

F Charih, KK Biggar, JR Green - Scientific Reports, 2022 - nature.com
Engineering peptides to achieve a desired therapeutic effect through the inhibition of a
specific target activity or protein interaction is a non-trivial task. Few of the existing in silico …

Mining audiograms to improve the interpretability of automated audiometry measurements

F Charih, M Bromwich, R Lefrançois… - 2018 IEEE …, 2018 - ieeexplore.ieee.org
Many people with hearing loss are unaware of it and do not seek benefit from available
interventions such as hearing aids. This is in part due to the limited accessibility to qualified …

Audiogram Digitization Tool for Audiological Reports

F Charih, JR Green - IEEE Access, 2022 - ieeexplore.ieee.org
Multiple private and public insurers compensate workers whose hearing loss can be directly
attributed to excessive exposure to noise in the workplace. The claim assessment process …

Gas prices of america: The machine-augmented crowd-sourcing era

K Dick, F Charih, J Woo… - 2020 17th Conference on …, 2020 - ieeexplore.ieee.org
Google Street View (GSV) comprises the largest collection of vehicle-based imagery of the
natural environment. With high spatial resolution, GSV has been widely adopted to study the …

Crystal structure of Campylobacter jejuni peroxide regulator

S Sarvan, F Charih, J Butcher, JS Brunzelle… - FEBS …, 2018 - Wiley Online Library
In Campylobacter jejuni (Cj), the metal‐cofactored peroxide response regulator (PerR)
transcription factor allows C. jejuni to respond to oxidative stresses. The crystal structure of the …