User profiles for Francesc Artigas

Francesc Artigas

Professor "Ad Honorem" Inst. d'InvestigacionsBiomèdiques de Barcelona, CSIC-IDIBAPS …
Verified email at iibb.csic.es
Cited by 24422

Acceleration of the effect of selected antidepressant drugs in major depression by 5-HT1A antagonists

F Artigas, L Romero, C de Montigny, P Blier - Trends in neurosciences, 1996 - cell.com
At clinically relevant doses, selective serotonin (5-HT) reuptake inhibitors (SSRIs) and MAO
inhibitors (MAOIs) increase the extracellular concentration of 5-HT in the midbrain raphé …

The therapeutic role of 5-HT1A and 5-HT2A receptors in depression

…, MV Puig, M Amargós-Bosch, A Adell, F Artigas - Journal of psychiatry and …, 2004 - jpn.ca
The selective serotonin reuptake inhibitors (SSRIs) are the most frequently prescribed
antidepressant drugs, because they are well tolerated and have no severe side effects. They …

Control of dorsal raphe serotonergic neurons by the medial prefrontal cortex: involvement of serotonin-1A, GABAA, and glutamate receptors

…, JM Casanovas, G Guillazo, F Artigas - Journal of …, 2001 - Soc Neuroscience
Anatomical evidence indicates that medial prefrontal cortex (mPFC) neurons project to the
dorsal raphe nucleus (DR). In this study, we functionally characterized this descending …

[HTML][HTML] Vortioxetine, a novel antidepressant with multimodal activity: review of preclinical and clinical data

C Sanchez, KE Asin, F Artigas - Pharmacology & therapeutics, 2015 - Elsevier
Vortioxetine, a novel antidepressant for the treatment of major depressive disorder (MDD),
is a 5-HT 3 , 5-HT 7 and 5-HT 1D receptor antagonist, 5-HT 1B receptor partial agonist, 5-HT …

Expression of Serotonin1A and Serotonin2A Receptors in Pyramidal and GABAergic Neurons of the Rat Prefrontal Cortex

…, A Bortolozzi, J Serrats, G Mengod, F Artigas - Cerebral …, 2004 - academic.oup.com
Serotonergic 5-HT 1A and 5-HT 2A receptors are abundantly expressed in prefrontal cortex (PFC)
and are targets of atypical antipsychotic drugs. They mediate, respectively, inhibitory …

Pindolol induces a rapid improvement of depressed patients treated with serotonin reuptake inhibitors

F Artigas, V Perez, E Alvarez - Archives of general psychiatry, 1994 - jamanetwork.com
Preclinical evidence indicates that repeated treatment with antidepressant drugs (serotonin [5-HT]
reuptake or monoamine oxidase [MAO] inhibitors) potentiates the ascending brain …

Co-expression and In Vivo Interaction of Serotonin1A and Serotonin2A Receptors in Pyramidal Neurons of Prefrontal Cortex

…, A Adell, P Celada, M Toth, G Mengod, F Artigas - Cerebral …, 2004 - academic.oup.com
The prefrontal cortex plays a key role in the control of higher brain functions and is involved
in the pathophysiology and treatment of schizophrenia. Here we report that ∼60% of the …

[HTML][HTML] Serotonin modulation of cortical neurons and networks

P Celada, MV Puig, F Artigas - Frontiers in integrative neuroscience, 2013 - frontiersin.org
The serotonergic pathways originating in the dorsal and median raphe nuclei (DR and MnR,
respectively) are critically involved in cortical function. Serotonin (5-HT), acting on …

Control of serotonergic function in medial prefrontal cortex by serotonin-2A receptors through a glutamate-dependent mechanism

…, DA Shapiro, BL Roth, G Mengod, F Artigas - Journal of …, 2001 - Soc Neuroscience
We examined the in vivo effects of the hallucinogen 4-iodo-2,5-dimethoxyamphetamine (DOI).
DOI suppressed the firing rate of 7 of 12 dorsal raphe (DR) serotonergic (5-HT) neurons …