The intimate connection between the brain and the heart was enunciated by Claude Bernard
over 150 years ago. In our neurovisceral integration model we have tried to build on this …

Anxiety disorders are highly prevalent and disabling but seem particularly tractable to
investigation with translational neuroscience methodologies. Neuroimaging has informed our …

Preparedness theory is one of the most influential ideas in explaining the origin of specific
phobias. The theory proposes that fear conditioning is selective to animals that have posed a …

Placebo may yield beneficial effects that are indistinguishable from those of active medication,
but the factors underlying proneness to respond to placebo are widely unknown. Here, we …

BACKGROUND: Evidence is accumulating that pharmacological blockade of the substance
P preferring neurokinin-1 (NK1) receptor reduces anxiety. This study compared the effects of …

This study investigated the effects of anxiety on nonverbal aspects of speech using data
collected in the framework of a large study of social phobia treatment. The speech of social …

Importance Serotonin is involved in negative affect, but whether anxiety syndromes, such as
social anxiety disorder (SAD), are characterized by an overactive or underactive serotonin …

Identifying brain systems that regulate or modulate autonomic nervous system functions
may identify pathways through which psychosocial factors can influence health and disease. …

The objective was to study effects of fear on brain activity, functional connectivity and brain-behavior
relationships during symptom provocation in subjects with specific phobia. Positron …

The inferior longitudinal fascicle (ILF) is one of the major occipital-temporal association
pathways. Several studies have mapped its hierarchical segmentation to specific functions. …