Imaging biomarkers (IBs) are integral to the routine management of patients with cancer. IBs
used daily in oncology include clinical TNM stage, objective response and left ventricular …

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is now frequently
used in early clinical trial assessment of antiangiogenic and vascular disrupting compounds. …

Tumors exhibit genomic and phenotypic heterogeneity, which has prognostic significance
and may influence response to therapy. Imaging can quantify the spatial variation in …

Rapid T 1 ‐weighted 3D spoiled gradient‐echo (GRE) data sets were acquired in the
abdomen of 23 cancer patients during a total of 113 separate visits to allow dynamic contrast‐…

This paper proposes and tests a technique for imaging orientationally invariant indices of
axon diameter and density in white matter using diffusion magnetic resonance imaging. Such …

Detailed knowledge of the anatomy and connectivity pattern of cortico-basal ganglia circuits
is essential to an understanding of abnormal cortical function and pathophysiology …

… results are broadly similar to those of Parker et al. who also demonstrated larger volume
of connections, particularly to the temporal lobe, on the left than the right (Parker et al., 2005). …

About 100 early-phase clinical trials and investigator-led studies of targeted antivascular
therapies—both anti-angiogenic and vascular-targeting agents—have reported data derived …

This article reviews the application of dynamic contrast-enhanced magnetic resonance
imaging in both clinical studies and early-phase trials of angiogenesis inhibitors. Emphasis is …

A method is presented for determining paths of anatomical connection between regions of
the brain using magnetic resonance diffusion tensor information. Level set theory, applied …