Background The causes of obsessive-compulsive disorder (OCD) are as yet unknown.
Evidence of familial aggregation is one approach for investigating the role of genetics in the …

… Gerald Nestadt, MD Eric Hollander, MD …

BackgroundKnowledge of the prevalence and correlates of personality disorders in the
community is important for identifying treatment needs and for provision of psychiatric services.…

Obsessive-compulsive disorder (OCD) is a psychiatric condition first described 100 years
ago. 1 The pathognomic features of the disorder are persistent, intrusive, senseless thoughts …

Background: The familial relationship between obsessive–compulsive disorder (OCD) and “obsessive–compulsive
spectrum” disorders is unclear. This study investigates the …

Copy number variants (CNVs) have been strongly implicated in the genetic etiology of
schizophrenia (SCZ). However, genome-wide investigation of the contribution of CNV to risk has …

We report the results of two studies examining the genetic overlap between schizophrenia
and velocardiofacial syndrome. In study A, we characterize two interstitial deletions identified …

Schizophrenia is a common disorder characterized by psychotic symptoms; diagnostic criteria
have been established 1. Family, twin and adoption studies suggest that both genetic and …

Obsessive-compulsive disorder (OCD) is a common, debilitating neuropsychiatric illness
with complex genetic etiology. The International OCD Foundation Genetics Collaborative (…

Schizophrenia is a common disorder with high heritability and a 10-fold increase in risk to
siblings of probands. Replication has been inconsistent for reports of significant genetic …