Increase in serotonin-1A autoreceptors in the midbrain of suicide victims with major depression—postmortem evidence for decreased serotonin activity
CA Stockmeier, LA Shapiro, GE Dilley… - Journal of …, 1998 - Soc Neuroscience
It has been hypothesized that a deficit in serotonin may be a crucial determinant in the
pathophysiology of major depression. Serotonin-1A receptors are located on serotonin cell bodies …
pathophysiology of major depression. Serotonin-1A receptors are located on serotonin cell bodies …
Elevated levels of tyrosine hydroxylase in the locus coeruleus in major depression
MY Zhu, V Klimek, GE Dilley, JW Haycock… - Biological …, 1999 - Elsevier
Background: Levels of tyrosine hydroxylase (TH) are regulated in the noradrenergic locus
coeruleus (LC) in response to changes in the activity of LC neurons and in response to …
coeruleus (LC) in response to changes in the activity of LC neurons and in response to …
Serotonin1A receptors are increased in postmortem prefrontal cortex in schizophrenia
T Sumiyoshi, CA Stockmeier, JC Overholser, GE Dilley… - Brain research, 1996 - Elsevier
Serotonin-5-HT 1A receptors were measured with [ 3 H]8-hydroxy-2-(di-n-propyl)aminotetralin
([ 3 H]8-OH-DPAT) in postmortem prefrontal cortex of 12 pairs of subjects with …
([ 3 H]8-OH-DPAT) in postmortem prefrontal cortex of 12 pairs of subjects with …
Serotonin receptors in suicide victims with major depression
CA Stockmeier, GE Dilley, LA Shapiro… - …, 1997 - Elsevier
Serotonin 1A (5-HT 1A ) and serotonin 2A (5-HT 2A ) receptors in the brain have been
implicated in the pathophysiology of suicide. Brain samples were collected at autopsy from …
implicated in the pathophysiology of suicide. Brain samples were collected at autopsy from …
Alterations in phosphoinositide signaling and G-protein levels in depressed suicide brain
The function of the phosphoinositide signal transduction system and the levels of heterotrimeric
G-protein α-subunits were examined in postmortem prefrontal cortex regions (8/9) and …
G-protein α-subunits were examined in postmortem prefrontal cortex regions (8/9) and …
The serotonin transporter in the midbrain of suicide victims with major depression
…, L Shapiro-Kulnane, GE Dilley, L Friedman, E Balraj… - Biological …, 2000 - Elsevier
Background: The involvement of serotonin in depression and suicide has been proposed,
because major depression is successfully treated by medications that specifically block the …
because major depression is successfully treated by medications that specifically block the …
Selective increases in phosphoinositide signaling activity and G protein levels in postmortem brain from subjects with schizophrenia or alcohol dependence
…, CA Grimes, MA Pacheco, GE Dilley… - Journal of …, 1998 - Wiley Online Library
Comparisons of the activity of the G protein‐mediated phosphoinositide signal transduction
system and of G protein levels were made in two regions of frontal cortex from eight …
system and of G protein levels were made in two regions of frontal cortex from eight …
Quantitative distribution of monoamine oxidase A in brainstem monoamine nuclei is normal in major depression
GA Ordway, JT Farley, GE Dilley, JC Overholser… - Brain research, 1999 - Elsevier
An abnormal expression of noradrenergic proteins (eg, tyrosine hydroxylase, norepinephrine
transporters) in the locus coeruleus has recently been demonstrated in subjects with major …
transporters) in the locus coeruleus has recently been demonstrated in subjects with major …
[CITATION][C] Phosphoinositide signaling activity in postmortem brain from subjects with schizophrenia or alcohol dependence
CA Stockmeier, L Song, GE Dilley, HY Meltzer… - Schizophrenia …, 1997 - infona.pl
… Stockmeier, Ling Song, Ginny E. Dilley, Herbert Y. Meltzer, James C. Overholser, Richard S. …
Reduced levels of norepinephrine transporters in the locus coeruleus in major depression
…, HY Meltzer, S Kalka, G Dilley… - Journal of …, 1997 - Soc Neuroscience
The norepinephrine transporter (NET) is a membrane protein responsible for termination of
the action of synaptic norepinephrine and is a site of action of many drugs used to treat major …
the action of synaptic norepinephrine and is a site of action of many drugs used to treat major …