Objetivo Avaliar a prevalência de transtornos ansiosos e fatores associados em uma amostra
populacional de idosos do Sul de Santa Catarina. Métodos Estudo transversal com base …

Psychiatric disorders, including major depressive disorder (MDD), bipolar disorder (BD) and
schizophrenia, affect a significant percentage of the world population. These disorders are …

The incidence of depressive illness is high worldwide, and the inadequacy of currently available
drug treatments contributes to the significant health burden associated with depression. …

Despite the revolution in recent decades regarding monoamine involvement in the
management of major depressive disorder (MDD), the biological mechanisms underlying this …

Ketamine is a non-competitive antagonist to the phencyclidine site of N-methyl-d-aspartate (NMDA)
receptor. Clinical findings point to a rapid onset of action for ketamine on the …

Major depression is characterized for symptoms at the psychological, behavioral and
physiological levels. The chronic mild stress model has been used as an animal model of …

Objective: Previous studies have suggested that oxidative stress may play a role in the
pathophysiology of bipolar disorder (BD). Moreover, recent studies indicate that lithium and …

Several studies have supported the idea that ionotropic glutamate N-methyl-d-aspartate
receptor (NMDA) is an important player in the etiology of psychopathologies, such as anxiety …

There is an emerging body of data suggesting that mood disorders are associated with
decreased brain-derived neurotrophic factor (BDNF). The present study aims to investigate the …

Abstract Treatment-resistant depression affects up to 20% of individuals suffering from
major depressive disorder (MDD). The medications currently available to treat depression, …