The purpose of this study was to characterize a new chemical entity, desvenlafaxine succinate
(DVS). DVS is a novel salt form of the isolated major active metabolite of venlafaxine. …

Background. Despite cancer patients preferring to spend their last days out-of-hospital, many
make difficult visits to the emergency department (ED). Family physician continuity of care …

Background: Although many patients with cancer would prefer to die at home, most die in
hospital. We carried out a study to describe the yearly trends in the place of death between …

This study is concerned with methods to measure population-based indicators of quality end-of-life
care. Using a retrospective cohort approach, we assessed the feasibility, validity and …

Background: Inequalities in access to palliative care programs (PCP) by age have been shown
to exist in Canada and elsewhere. Few studies have been able to provide greater insight …

Persons with limited life expectancy (LLE) – less than 1 year – are significant consumers of
health care, are at increased risk of polypharmacy and adverse drug events, and have …

BACKGROUND Quality indicators (QIs) are tools designed to measure and improve quality
of care. The objective of this study was to assess stakeholder acceptability of QIs of end‐of‐…

Background Paracetamol (acetaminophen) is generally considered a safe medication, but is
associated with hepatotoxicity at doses above doses of 4.0g/day, and even below this daily …

Background: Fulfillment of patient preferences for location of dying is of continued end-of-life
care interest. Of those voicing a preference, most prefer home. However the majority of …

Background: Continuity of primary care is known to be associated with both improved
processes and outcomes of care. Despite continuity being a desired attribute of end-of-life care …