Increased p38-MAPK is responsible for chemotherapy resistance in human gastric cancer cells

…, J Song, X Bu, Y Cheng, K Sun, H Xiong, G Jiang… - BMC cancer, 2008 - Springer
Background Chemoresistance is one of the main obstacles to successful cancer therapy and
is frequently associated with Multidrug resistance (MDR). Many different mechanisms have …

Mesenchymal stem cells in inflammation microenvironment accelerates hepatocellular carcinoma metastasis by inducing epithelial-mesenchymal transition

Y Jing, Z Han, Y Liu, K Sun, S Zhang, G Jiang, R Li… - 2012 - journals.plos.org
In response to inflammation, mesenchymal stem cells (MSCs) are known to migrate to tissue
injury sites to participate in immune modulation, tissue remodeling and wound healing. …

Immunosuppressive effect of bone marrow‐derived mesenchymal stem cells in inflammatory microenvironment favours the growth of B16 melanoma cells

Z Han, Z Tian, G Lv, L Zhang, G Jiang… - Journal of cellular …, 2011 - Wiley Online Library
Mesenchymal stem cells (MSCs) are studied for their potential clinical use in regenerative
medicine, tissue engineering and tumour therapy. However, the therapeutic application of …

Interleukin 7 receptor activates PI3K/Akt/mTOR signaling pathway via downregulation of Beclin‐1 in lung cancer

…, D Zhiying, J Yanduo, J Guocheng - Molecular …, 2019 - Wiley Online Library
Interleukin‐7(IL‐7) can regulate proliferation and apoptosis of cell and also regulate tumor
lymphangiogenesis, but whether it regulating autophagy of tumor cells is not well known. We …

Effects of inflammatory factors on mesenchymal stem cells and their role in the promotion of tumor angiogenesis in colon cancer

…, S Zhang, Y Jing, X Bu, C Wang, K Sun, G Jiang… - Journal of Biological …, 2011 - ASBMB
Mesenchymal stem cells (MSCs), which are modulated by cytokines present in the tumor
microenvironment, play an important role in tumor progression. It is well documented that …

CpG island methylator phenotype association with upregulated telomerase activity in hepatocellular carcinoma

C Zhang, X Guo, G Jiang, L Zhang… - … journal of cancer, 2008 - Wiley Online Library
CpG island methylator phenotype (CIMP) involves the targeting of multiple genes by promoter
hypermethylation. Telomerase plays an important role in the development of cellular …

Interleukin-7 up-regulates cyclin D1 via activator protein-1 to promote proliferation of cell in lung cancer

J Ming, G Jiang, Q Zhang, X Qiu, E Wang - Cancer immunology …, 2012 - Springer
Interleukin-7 is a potent regulator of lymphocyte proliferation, but it inducing growth of solid
tumors is few known. We study the relationship between Interleukin-7 and the regulator of the …

Tumor necrosis factor-alpha promotes tumor growth by inducing vascular endothelial growth factor

Y Jing, N Ma, T Fan, C Wang, X Bu, G Jiang… - Cancer …, 2011 - Taylor & Francis
Tumor necrosis factor (TNF)-α has been proved as an adjuvant therapy for tumor by FDA.
However, the effect of chronic TNF-α expression for tumor is still controversial. In this study, we …

Correlation of CpG island methylator phenotype with poor prognosis in hepatocellular carcinoma

…, J Zhao, C Wang, Y Xu, Z Han, G Jiang… - … and molecular pathology, 2010 - Elsevier
CpG island methylator phenotype (CIMP), in which multiple genes are concurrently methylated,
is an important mechanism in hepatocellular carcinoma development. We determined a …

Deformation control techniques for 200 m-high Hongjiadu concrete face rockfill dam

Y Zeyan, J Guocheng - Chinese Journal of Geotechnical …, 2008 - cgejournal.com
With regard to the existing problems in 200 m-high concrete face rockfill dams (CFRD) and
combined with the characteristics of Hongjiadu CFRD project, a study was performed on the …