New agents with particular specificity toward targeted bacteria and superefficacy in antibacterial
activity are urgently needed in facing the crisis of worldwide antibiotic resistance. Herein…

Efficient signal amplification is essential to construct ultrasensitive biosensors for biologically
relevant species with abundant concomitant interferences. Here, we apply LbaCas12a as a …

In eukaryotic cells, autophagy is a highly conserved self-digestion process to promote cell
survival in response to nutrient starvation and other metabolic stresses. Autophagy is …

Background Characterizing drug interactions using a response surface allows for the
determination of the interaction over a complete range of clinically relevant concentrations. …

A sensitive and selective electrochemical DNA sensor was developed for the detection of
BCR/ABL fusion gene in chronic myelogenous leukemia (CML). Firstly, graphene sheets (GS) …

Background: We conducted a systematic review and meta-analysis to determine the association
between serum lipid levels and suicidality, as evidence from previous studies has been …

Background We conducted a systematic review and meta-analysis to summarize the current
evidence on the relationship between family history of autoimmune diseases (ADs) and risk …

Background The extent to which complex auditory stimuli are processed and differentiated
during general anesthesia is unknown. The authors used blood oxygenation level-dependent …

A sensitive electrochemical biosensor was developed to detect toxin A (TOA) of Clostridium
difficile based on an aptamer selected by the systematic evolution of ligands using …

Circulating tumor cells (CTCs) contain a great deal of information of tumor phenotype.
Therefore, highly sensitive detection and specific enrichment of CTCs are of intense interest. …