Genome-wide association studies (GWAS) have now identified at least 2,000 common
variants that appear associated with common diseases or related traits ( http://www.genome.gov/…

In comparison to severe acute respiratory syndrome coronavirus (SARS-CoV), SARS-CoV-2
appears to be more contagious [1], and coronavirus disease 2019 (COVID-19) patients …

Objectives: To determine whether genotypes at CLU, PICALM, and CR1 confer risk for
Alzheimer disease (AD) and whether risk for AD associated with these genes is influenced by …

Previous genome-wide association (GWA) studies typically focus on single-locus analysis,
which may not have the power to detect the majority of genuinely associated loci. Here, we …

Background Neuroblastoma is a malignant condition of the developing sympathetic nervous
system that most commonly affects young children and is often lethal. Its cause is not known…

Neuroblastoma is a childhood cancer of the sympathetic nervous system that accounts for
approximately 10% of all paediatric oncology deaths 1 , 2 . To identify genetic risk factors for …

Neuroblastoma is a cancer of the sympathetic nervous system that accounts for approximately
10% of all pediatric oncology deaths 1 . Here, we report a genome-wide association study …

High-throughput sequencing platforms are generating massive amounts of genetic variation
data for diverse genomes, but it remains a challenge to pinpoint a small subset of …

Crohn’s disease and ulcerative colitis, the two common forms of inflammatory bowel disease
(IBD), affect over 2.5 million people of European ancestry, with rising prevalence in other …

Eleven susceptibility loci for late-onset Alzheimer's disease (LOAD) were identified by previous
studies; however, a large portion of the genetic risk for this disease remains unexplained. …