[HTML][HTML] microRNA modulation of circadian-clock period and entrainment
HYM Cheng, JW Papp, O Varlamova, H Dziema… - Neuron, 2007 - cell.com
microRNAs (miRNAs) are a class of small, noncoding RNAs that regulate the stability or
translation of mRNA transcripts. Although recent work has implicated miRNAs in development …
translation of mRNA transcripts. Although recent work has implicated miRNAs in development …
Somatic and Occult Germ-line Mutations in SDHD, a Mitochondrial Complex II Gene, in Nonfamilial Pheochromocytoma
O Gimm, M Armanios, H Dziema, HPH Neumann… - Cancer research, 2000 - AACR
Most pheochromocytomas are sporadic but about 10% are thought to be hereditary. Although
the etiology of most inherited pheochromocytoma is well known, little is known about the …
the etiology of most inherited pheochromocytoma is well known, little is known about the …
[HTML][HTML] The p42/44 mitogen-activated protein kinase pathway couples photic input to circadian clock entrainment
GQ Butcher, H Dziema, M Collamore… - Journal of Biological …, 2002 - ASBMB
In mammals, the suprachiasmatic nuclei (SCN) of the hypothalamus function as the major
biological clock. SCN-dependent rhythms of physiology and behavior are regulated by …
biological clock. SCN-dependent rhythms of physiology and behavior are regulated by …
The ERK/MAP kinase pathway couples light to immediate‐early gene expression in the suprachiasmatic nucleus
H Dziema, B Oatis, GQ Butcher, R Yates… - European Journal of …, 2003 - Wiley Online Library
Signalling via the p42/44 mitogen‐activated protein kinase (MAPK) pathway has been identified
as an intermediate event coupling light to entrainment of the mammalian circadian clock …
as an intermediate event coupling light to entrainment of the mammalian circadian clock …
Modulation of learning and memory by the targeted deletion of the circadian clock gene Bmal1 in forebrain circuits
KH Price, H Dziema, S Aten, J Loeser… - Behavioural brain …, 2016 - Elsevier
A large body of literature has shown that the disruption of circadian clock timing has profound
effects on mood, memory and complex thinking. Central to this time keeping process is the …
effects on mood, memory and complex thinking. Central to this time keeping process is the …
Circadian regulation of mammalian target of rapamycin signaling in the mouse suprachiasmatic nucleus
R Cao, FE Anderson, YJ Jung, H Dziema, K Obrietan - Neuroscience, 2011 - Elsevier
Circadian (24-h) rhythms influence virtually every aspect of mammalian physiology. The
main rhythm generation center is located in the suprachiasmatic nucleus (SCN) of the …
main rhythm generation center is located in the suprachiasmatic nucleus (SCN) of the …
The molecular gatekeeper Dexras1 sculpts the photic responsiveness of the mammalian circadian clock
HYM Cheng, H Dziema, J Papp, DP Mathur… - Journal of …, 2006 - Soc Neuroscience
The mammalian master clock, located in the suprachiasmatic nucleus (SCN), is exquisitely
sensitive to photic timing cues, but the key molecular events that sculpt both the phasing and …
sensitive to photic timing cues, but the key molecular events that sculpt both the phasing and …
CRE-mediated transcription and COX-2 expression in the pilocarpine model of status epilepticus
B Lee, H Dziema, KH Lee, YS Choi, K Obrietan - Neurobiology of disease, 2007 - Elsevier
Status epilepticus (SE) triggers neuronal death, reactive gliosis and remodeling of synaptic
circuitry, thus leading to profound pathological alterations in CNS physiology. These …
circuitry, thus leading to profound pathological alterations in CNS physiology. These …
Proteomic profiling of the epileptic dentate gyrus
A Li, YS Choi, H Dziema, R Cao, HY Cho… - Brain …, 2010 - Wiley Online Library
The development of epilepsy is often associated with marked changes in central nervous
system cell structure and function. Along these lines, reactive gliosis and granule cell axonal …
system cell structure and function. Along these lines, reactive gliosis and granule cell axonal …
Segregation of expression of mPeriod gene homologs in neurons and glia: possible divergent roles of mPeriod1 and mPeriod2 in the brain
…, M Alvarez-Saavedra, H Dziema… - Human molecular …, 2009 - academic.oup.com
The suprachiasmatic nuclei (SCN) of the mammalian hypothalamus function as the master
circadian clock, coordinating the timing of diverse cell populations and organ systems. …
circadian clock, coordinating the timing of diverse cell populations and organ systems. …