Fear can be acquired vicariously through social observation of others suffering from aversive
stimuli. We found that mice (observers) developed freezing behavior by observing other …

T-type Ca 2+ currents have been proposed to be involved in the genesis of spike-and-wave
discharges, a sign of absence seizures, but direct evidence in vivo to support this hypothesis …

Low-voltage-activated T-type Ca 2+ channels are widely expressed in various types of neurons.
Once deinactivated by hyperpolarization, T-type channels are ready to be activated by a …

While the interaction of the cardinal rhythms of non-rapid-eye-movement (NREM) sleep—the
thalamo-cortical spindles, hippocampal ripples, and the cortical slow oscillations—is …

During development of the cerebral cortex, the invasion of thalamic axons and subsequent
differentiation of cortical neurons are tightly coordinated. Here we provide evidence that …

Sensations from viscera, like fullness, easily become painful if the stimulus persists. Mice
lacking α1G T-type Ca 2+ channels show hyperalgesia to visceral pain. Thalamic infusion of a T…

Calcium (Ca 2+ ) signals that are precisely modulated in space and time mediate a myriad of
cellular processes, including contraction, excitation, growth, differentiation and apoptosis 1 …

We report the construction of a genetic linkage map of the mouse, consisting entirely of
genetic markers that can be rapidly typed by polymerase chain reaction and that show a high …

Observational fear learning in rodents is a type of context-dependent fear conditioning in
which an unconditioned stimulus (US) is provided vicariously by observing conspecific others …

Synaptic inhibition is based on both tonic and phasic release of the inhibitory transmitter γ-aminobutyric
acid (GABA). Although phasic GABA release arises from Ca 2+ -dependent …