Immunocytochemistry for choline acetyltransferase (ChAT) and the vesicular acetylcholine
transporter (VAChT) was used to examine the expression of these linked cholinergic markers …

Glutamate transport into synaptic vesicles is a prerequisite for its regulated neurosecretion.
Here we functionally identify a second isoform of the vesicular glutamate transporter (VGLUT2…

The vesicular acetylcholine transporter (VAChT) has been identified and characterized
based on the acquisition of high affinity vesamicol binding and proton-dependent, vesamicol-…

A fundamental question in synaptic physiology is whether the unitary strength of a synapse
can be regulated by presynaptic characteristics and, if so, what those characteristics might be…

Glutamine is the preferred precursor for the neurotransmitter pool of glutamate, the major
excitatory transmitter in the mammalian central nervous system. We have isolated a …

Glutamine, the preferred precursor for neurotransmitter glutamate and GABA, is likely to be
the principal substrate for the neuronal System A transporter SNAT1 in vivo. We explored the …

A cDNA clone encoding a plasma membrane alanine-preferring transporter (SAT2) has been
isolated from glutamatergic neurons in culture and represents the second member of the …

We have cloned and functionally characterized a third isoform of a vesicular glutamate
transporter (VGLUT3) expressed on synaptic vesicles that identifies a distinct glutamatergic …

Homeostatic control of pyramidal neuron firing rate involves a functional balance of feedforward
excitation and feedback inhibition in neocortical circuits. Here, we reveal a dynamic …

The characteristics of ATP-dependent transport of acetylcholine (ACh) in homogenates of
pheochromocytoma (PC-12) cells stably transfected with the human vesicular acetylcholine …