User profiles for Hiroyuki Nawa
 | Hiroyuki NawaDepartment of Physiological Sciences, School of Pharmaceutical Sciences, Wakayama … Verified email at wakayama-med.ac.jp Cited by 20557 |
Cytokine hypothesis of schizophrenia pathogenesis: evidence from human studies and animal models
Y Watanabe, T Someya, H Nawa - Psychiatry and clinical …, 2010 - Wiley Online Library
The pathogenesis of schizophrenia has yet to be fully characterized. Gene–environment
interactions have been found to play a crucial role in the vulnerability to this disease. Among …
interactions have been found to play a crucial role in the vulnerability to this disease. Among …
BDNF protein measured by a novel enzyme immunoassay in normal brain and after seizure: partial disagreement with mRNA levels
Messenger RNA for brain‐derived neurotrophic factor (BDNF) is distributed in many brain
regions and regulated by excitatory neuronal activity. Despite numerous studies of BDNF …
regions and regulated by excitatory neuronal activity. Despite numerous studies of BDNF …
Regional specificity of alterations in NGF, BDNF and NT-3 levels in Alzheimer's disease
…, K Wakabayashi, S Tsuji, H Takahashi, H Nawa - …, 1996 - journals.lww.com
USING two-site enzyme immunoassays (EIAs), we measured the levels of neurotrophins,
nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3) …
nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3) …
Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects
…, K Agerman, A Haapasalo, H Nawa… - Journal of …, 2003 - Soc Neuroscience
Recent studies have indicated that exogenously administered neurotrophins produce
antidepressant-like behavioral effects. We have here investigated the role of endogenous brain-…
antidepressant-like behavioral effects. We have here investigated the role of endogenous brain-…
Molecular characterization of a novel retinal metabotropic glutamate receptor mGluR6 with a high agonist selectivity for L-2-amino-4-phosphonobutyrate
Y Nakajima, H Iwakabe, C Akazawa, H Nawa… - Journal of Biological …, 1993 - Elsevier
A cDNA clone for a new metabotropic glutamate receptor, termed mGluR6, was isolated from
a rat retinal cDNA library by cross-hybridization with the previously isolated cDNA clone for …
a rat retinal cDNA library by cross-hybridization with the previously isolated cDNA clone for …
Brain-derived neurotrophic factor induces mammalian target of rapamycin-dependent local activation of translation machinery and protein synthesis in neuronal …
…, H Namba, K Hara, K Yonezawa, H Nawa - Journal of …, 2004 - Soc Neuroscience
In neurons, perisynaptic or dendritic translation is implicated in synapse-wide alterations of
function and morphology triggered by neural activity. The molecular mechanisms controlling …
function and morphology triggered by neural activity. The molecular mechanisms controlling …
Nucleotide sequences of cloned cDNAs for two types of bovine brain substance P precursor
H Nawa, T Hirose, H Takashima, S Inayama… - Nature, 1983 - nature.com
The primary structures of two types of bovine brain substance P precursors have been
determined. One precursor contains a sequence homologous to that of the amphibian peptide …
determined. One precursor contains a sequence homologous to that of the amphibian peptide …
[HTML][HTML] Increased l1 retrotransposition in the neuronal genome in schizophrenia
Recent studies indicate that long interspersed nuclear element-1 (L1) are mobilized in the
genome of human neural progenitor cells and enhanced in Rett syndrome and ataxia …
genome of human neural progenitor cells and enhanced in Rett syndrome and ataxia …
[HTML][HTML] Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transduction.
T Abe, H Sugihara, H Nawa, R Shigemoto… - Journal of Biological …, 1992 - Elsevier
A cDNA clone for a new metabotropic glutamate receptor, mGluR5, was isolated through
polymerase chain reaction-mediated DNA amplification by using primer sequences conserved …
polymerase chain reaction-mediated DNA amplification by using primer sequences conserved …
Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats
Brain-derived neurotrophic factor (BDNF) regulates both short-term synaptic functions and
activity-dependent synaptic plasticity such as long-term potentiation. In the present study, we …
activity-dependent synaptic plasticity such as long-term potentiation. In the present study, we …