The impact of accelerated HF-rTMS on the subgenual anterior cingulate cortex in refractory unipolar major depression: insights from 18FDG PET brain imaging

…, GR Wu, C Van Hove, K Audenaert, I Goethals… - Brain stimulation, 2015 - Elsevier
Background Although one of the most frequent diagnosed mental illnesses worldwide, it
appears to be challenging to successfully treat major depressive disorder (MDD). Although the …

Decreased 5-HT2a receptor binding in patients with anorexia nervosa

…, F Dumont, M Vervaet, I Goethals… - Journal of Nuclear …, 2003 - Soc Nuclear Med
Indirect estimations of brain neurotransmitters in patients with anorexia nervosa (AN) and
low weight have demonstrated a reduction in brain serotonin (5-HT) turnover in general and …

PET with 18F-labelled choline-based tracers for tumour imaging: a review of the literature

…, B Lambert, M Acou, F De Vos, I Goethals - European journal of …, 2010 - Springer
Purpose To give an up-to-date overview of the potential clinical utility of 18 F-labelled choline
derivatives for tumour imaging with positron emission tomography. Methods A PubMed …

SPECT neuropsychological activation procedure with the Verbal Fluency Test in attempted suicide patients

K Audenaert, I Goethals, K Van Laere… - Nuclear Medicine …, 2002 - journals.lww.com
Performance on the Verbal Fluency Test, as a measure of the ability of initiating processes,
is reduced in depressed suicidal patients. The hampered results in this prefrontal executive …

The impact of HF-rTMS treatment on serotonin2A receptors in unipolar melancholic depression

…, J Mertens, A Dobbeleir, P Blanckaert, I Goethals - Brain stimulation, 2011 - Elsevier
Background Currently, the underlying neurobiological mechanism as to how repetitive
transcranial magnetic stimulation (rTMS) can alter depressive states remains unclear. Animal data …

Age-related differences in metabolites in the posterior cingulate cortex and hippocampus of normal ageing brain: a 1H-MRS study

…, Y De Deene, K Audenaert, I Goethals… - European journal of …, 2012 - Elsevier
OBJECTIVE: To study age-related metabolic changes in N-acetylaspartate (NAA), total
creatine (tCr), choline (Cho) and myo-inositol (Ins). MATERIALS AND METHODS: Proton …

Gastrin-releasing peptide receptor imaging in human breast carcinoma versus immunohistochemistry

…, P Phonteyne, P Pauwels, I Goethals… - Journal of Nuclear …, 2008 - Soc Nuclear Med
This study reports on the uptake of 99m Tc-RP527 by human breast carcinoma and its
relationship to gastrin-releasing peptide receptor (GRP-R) expression as measured by …

Machine learning based brain tumour segmentation on limited data using local texture and abnormality

S Bonte, I Goethals, R Van Holen - Computers in biology and medicine, 2018 - Elsevier
Brain tumour segmentation in medical images is a very challenging task due to the large
variety in tumour shape, position, appearance, scanning modalities and scanning parameters. …

Brain perfusion SPECT in impulsivity-related personality disorders

I Goethals, K Audenaert, F Jacobs… - Behavioural brain …, 2005 - Elsevier
BACKGROUND:: Impulsive behaviours in patients with cluster B personality disorders are
associated with low glucose metabolism and regional cerebral blood flow in the frontal cortex …

Imaging of the 5-HT2A system: age-, gender-, and Alzheimer's disease-related findings

…, D Decoo, M Vandecapelle, P Santens, I Goethals… - Neurobiology of …, 2003 - Elsevier
Serotonin (5-HT) and more specifically the 5-HT 2A receptor is involved in cognitive and non-cognitive
behavior and plays an important role in Alzheimer’s disease (AD). The objective …