Positron emission tomography (PET) findings suggesting lower D 2 -type dopamine receptors
and dopamine concentration in brains of stimulant users have prompted speculation that …

See Jellinger (doi: 10.1093/awx190 ) for a scientific commentary on this article. The enzyme
monoamine oxidases (B and A subtypes, encoded by MAOB and MAOA, respectively) are …

Eight healthy men underwent two positron emission tomography (PET) [ 11 C]raclopride
scans, one following placebo, the second following d-amphetamine (0.30 mg/kg, po). PET data …

The objective of this review is to evaluate the evidence that recreational methamphetamine
exposure might damage dopamine neurones in human brain, as predicted by experimental …

Gambling disorder (GD) was reclassified as a behavioral addiction in the DSM-5 and shares
clinical and behavioral features with substance use disorders (SUDs). Neuroimaging …

Drugs that increase dopamine levels in the brain can cause psychotic symptoms in healthy
individuals and worsen them in schizophrenic patients. Psychological stress also increases …

Objective: Clinical investigators in Japan have long suggested that exposure to methamphetamine
might cause a persistent schizophrenia-like psychosis. This possibility is discounted …

Microdialysis experiments in rodents indicate that ethanol promotes dopamine release
predominantly in the nucleus accumbens, a phenomenon that is implicated in the reinforcing …

The dopamine system is a primary treatment target for cocaine dependence (CD), but research
on dopaminergic abnormalities (eg, D 2 receptor system deficiencies) has so far failed to …

Context In animals, repeated exposure to stimulant drugs leads to an enhanced drug-induced
psychomotor response and increased dopamine release. This phenomenon, known as …