CCK in anxiety and cognitive processes
V Daugé, I Léna - Neuroscience & Biobehavioral Reviews, 1998 - Elsevier
DAUGÉ, V. AND I. LÉNA. CCK in anxiety and cognitive processes. NEUROSCI BIOBEHAV
REV 22(6) 815–825, 1998.—Extensive studies were carried out on the involvement of the …
REV 22(6) 815–825, 1998.—Extensive studies were carried out on the involvement of the …
[HTML][HTML] Interaction with vesicle luminal protachykinin regulates surface expression of δ-opioid receptors and opioid analgesia
Opioid and tachykinin systems are involved in modulation of pain transmission in the spinal
cord. Regulation of surface opioid receptors on nociceptive afferents is critical for opioid …
cord. Regulation of surface opioid receptors on nociceptive afferents is critical for opioid …
[HTML][HTML] Ketamine, at a dose that disrupts motor behavior and latent inhibition, enhances prefrontal cortex synaptic efficacy and glutamate release in the nucleus …
F Razoux, R Garcia, I Léna - Neuropsychopharmacology, 2007 - nature.com
Noncompetitive N-methyl-D-aspartate (NMDA) antagonists such as ketamine represent
useful pharmacological tools to model, in both healthy humans and rodents, behavioral and …
useful pharmacological tools to model, in both healthy humans and rodents, behavioral and …
Prefrontal infusion of PD098059 immediately after fear extinction training blocks extinction‐associated prefrontal synaptic plasticity and decreases prefrontal ERK2 …
S Hugues, A Chessel, I Lena, R Marsault, R Garcia - Synapse, 2006 - Wiley Online Library
A previous study has demonstrated that disruption of fear extinction‐induced long‐term
potentiation (LTP) in the medial prefrontal cortex (mPFC) is associated with the return of fear …
potentiation (LTP) in the medial prefrontal cortex (mPFC) is associated with the return of fear …
5-hydroxytryptamine (5-HT) 1A autoreceptor adaptive changes in substance P (neurokinin 1) receptor knock-out mice mimic antidepressant-induced desensitization
…, AM Gardier, R Moratalla, I Alberti, I Lena… - Journal of …, 2001 - Soc Neuroscience
Antagonists at substance P receptors of the neurokinin 1 (NK1) type have been shown to
represent a novel class of antidepressant drugs, with comparable clinical efficacy to the …
represent a novel class of antidepressant drugs, with comparable clinical efficacy to the …
Rat hippocampal neurons are critically involved in physiological improvement of memory processes induced by cholecystokinin-B receptor stimulation
A Sebret, I Léna, D Crété, T Matsui… - Journal of …, 1999 - Soc Neuroscience
The involvement in memory processes of the neuropeptide cholecystokinin (CCK) through
its interaction with the CCK-B receptors was studied. The two-trial recognition memory task …
its interaction with the CCK-B receptors was studied. The two-trial recognition memory task …
[HTML][HTML] NaV1.2 haploinsufficiency in Scn2a knock-out mice causes an autistic-like phenotype attenuated with age
I Léna, M Mantegazza - Scientific reports, 2019 - nature.com
Mutations of the SCN2A gene, encoding the voltage gated sodium channel Na V 1.2, have
been associated to a wide spectrum of epileptic disorders ranging from benign familial …
been associated to a wide spectrum of epileptic disorders ranging from benign familial …
[PDF][PDF] The intracellular Na+/H+ exchanger NHE7 effects a Na+-coupled, but not K+-coupled proton-loading mechanism in endocytosis
N Milosavljevic, M Monet, I Léna, F Brau… - Cell reports, 2014 - cell.com
Vesicular H + -ATPases and ClC-chloride transporters are described to acidify intracellular
compartments, which also express the highly conserved Na + /H + exchangers NHE6, NHE7, …
compartments, which also express the highly conserved Na + /H + exchangers NHE6, NHE7, …
[HTML][HTML] Initiation of migraine-related cortical spreading depolarization by hyperactivity of GABAergic neurons and NaV1.1 channels
O Chever, S Zerimech, P Scalmani… - The Journal of …, 2021 - Am Soc Clin Investig
Spreading depolarizations (SDs) are involved in migraine, epilepsy, stroke, traumatic brain
injury, and subarachnoid hemorrhage. However, the cellular origin and specific differential …
injury, and subarachnoid hemorrhage. However, the cellular origin and specific differential …
Molecular and electrophysiological changes in the prefrontal cortex–amygdala–dorsal periaqueductal grey pathway during persistent pain state and fear-conditioned …
RK Butler, L Nilsson-Todd, C Cleren, I Léna… - Physiology & …, 2011 - Elsevier
Fear-conditioned analgesia (FCA) is the reduction in pain responding which is expressed
upon re-exposure to a context previously paired with an aversive stimulus. Projections along …
upon re-exposure to a context previously paired with an aversive stimulus. Projections along …