[HTML][HTML] Serum microRNA profiles in children with autism
M Mundalil Vasu, A Anitha, I Thanseem, K Suzuki… - Molecular autism, 2014 - Springer
Background As regulators of gene expression, microRNAs (miRNAs) play a key role in the
transcriptional networks of the developing human brain. Circulating miRNAs in the serum and …
transcriptional networks of the developing human brain. Circulating miRNAs in the serum and …
[HTML][HTML] Brain region-specific altered expression and association of mitochondria-related genes in autism
A Anitha, K Nakamura, I Thanseem, K Yamada… - Molecular autism, 2012 - Springer
Background Mitochondrial dysfunction (MtD) has been observed in approximately five
percent of children with autism spectrum disorders (ASD). MtD could impair highly energy-…
percent of children with autism spectrum disorders (ASD). MtD could impair highly energy-…
Downregulation of the expression of mitochondrial electron transport complex genes in autism brains
A Anitha, K Nakamura, I Thanseem… - Brain …, 2013 - Wiley Online Library
Mitochondrial dysfunction ( MtD ) and abnormal brain bioenergetics have been implicated
in autism, suggesting possible candidate genes in the electron transport chain ( ETC ). We …
in autism, suggesting possible candidate genes in the electron transport chain ( ETC ). We …
[HTML][HTML] Genetic affinities among the lower castes and tribal groups of India: inference from Y chromosome and mitochondrial DNA
Background India is a country with enormous social and cultural diversity due to its positioning
on the crossroads of many historic and pre-historic human migrations. The hierarchical …
on the crossroads of many historic and pre-historic human migrations. The hierarchical …
[HTML][HTML] In situ origin of deep rooting lineages of mitochondrial Macrohaplogroup 'M' in India
Background Macrohaplogroups 'M' and 'N' have evolved almost in parallel from a founder
haplogroup L3. Macrohaplogroup N in India has already been defined in previous studies and …
haplogroup L3. Macrohaplogroup N in India has already been defined in previous studies and …
[HTML][HTML] Decreased expression of axon-guidance receptors in the anterior cingulate cortex in autism
…, C Shimmura, Y Kameno, A Anitha, I Thanseem… - Molecular autism, 2011 - Springer
Background Axon-guidance proteins play a crucial role in brain development. As the dysfunction
of axon-guidance signaling is thought to underlie the microstructural abnormalities of …
of axon-guidance signaling is thought to underlie the microstructural abnormalities of …
Genetic analyses of Roundabout (ROBO) axon guidance receptors in autism
…, K Yamada, S Suda, I Thanseem… - American Journal of …, 2008 - Wiley Online Library
Autism is a pervasive developmental disorder diagnosed in early childhood. Abnormalities
of serotonergic neurotransmission have been reported in autism. Serotonin transporter (SERT…
of serotonergic neurotransmission have been reported in autism. Serotonin transporter (SERT…
Protocadherin α (PCDHA) as a novel susceptibility gene for autism
A Anitha, I Thanseem, K Nakamura, K Yamada… - Journal of Psychiatry and …, 2013 - jpn.ca
Background: Synaptic dysfunction has been shown to be involved in the pathogenesis of
autism. We hypothesized that the protocadherin α gene cluster (PCDHA), which is involved in …
autism. We hypothesized that the protocadherin α gene cluster (PCDHA), which is involved in …
miRNAs as biomarkers of neurodegenerative disorders
V Viswambharan, I Thanseem, MM Vasu… - Biomarkers in …, 2017 - Future Medicine
Neurodegenerative diseases (NDDs) are the result of progressive deterioration of neurons,
ultimately leading to disabilities. There is no effective cure for NDDs at present; ongoing …
ultimately leading to disabilities. There is no effective cure for NDDs at present; ongoing …
Telomeres in neurological disorders
A Anitha, I Thanseem, MM Vasu… - Advances in Clinical …, 2019 - Elsevier
Ever since their discovery, the telomeres and the telomerase have been topics of intensive
research, first as a mechanism of cellular aging and later as an indicator of health and …
research, first as a mechanism of cellular aging and later as an indicator of health and …