Task-free functional connectivity in animal models provides an experimental framework to
examine connectivity phenomena under controlled conditions and allows for comparisons …

Long-term cognitive deficits are observed after treatment of brain tumors or metastases by
radiotherapy. Treatment optimization thus requires a better understanding of the effects of …

Advances in digital whole-slide imaging and machine learning (ML) provide new opportunities
for automated examination and quantification of histopathological slides to support …

Task-free functional connectivity in animal models provides an experimental framework to
examine connectivity phenomena under controlled conditions and allows comparison with …

The logarithm of the octanol–water partition coefficient, logP, is a key physicochemical
property for both pharmaceutical drugs and agrochemicals. It is also required by legislation as …

O-(2- 18 F-fluoroethyl)-l-tyrosine ( 18 F-FET) is a radiolabeled artificial amino acid used in
PET for tumor delineation and grading. The present study compares different kinetic models to …

Purpose The radiation dose delivered to brain tumors is limited by the possibility to induce
vascular damage and necrosis in surrounding healthy tissue. In the present study, we …

Brain metastases are the most prevalent intracranial malignancy. Patient outcome is poor
and treatment options are limited. Hence, new avenues must be explored to identify potential …

Purpose To assess the effect of a variety of anesthetic regimes on ‐weighted MRI of the
mouse brain and to determine the optimal regimes to perform ‐weighted MRI of the mouse …

Knowledge of the arterial input function (AIF), that is, the concentration of a tracer in arterial
blood over time, is a prerequisite of most pharmacokinetic models used in quantitative PET. …