User profiles for J. Jean Chen

J. Jean Chen

University of Toronto
Verified email at research.baycrest.org
Cited by 3559

Age-associated reductions in cerebral blood flow are independent from regional atrophy

JJ Chen, HD Rosas, DH Salat - Neuroimage, 2011 - Elsevier
Prior studies have demonstrated decreasing cerebral blood flow (CBF) in normal aging, but
the full spatial pattern and potential mechanism of changes in CBF remain to be elucidated. …

Global cerebral oxidative metabolism during hypercapnia and hypocapnia in humans: implications for BOLD fMRI

JJ Chen, GB Pike - Journal of Cerebral Blood Flow & …, 2010 - journals.sagepub.com
The effect of carbon dioxide (CO 2 ) on cerebral metabolism is of tremendous interest to
functional imaging. In particular, mild-to-moderate hypercapnia is routinely used in calibrated …

BOLD‐specific cerebral blood volume and blood flow changes during neuronal activation in humans

JJ Chen, GB Pike - … : An International Journal Devoted to the …, 2009 - Wiley Online Library
To understand and predict the blood‐oxygenation level‐dependent (BOLD) fMRI signal, an
accurate knowledge of the relationship between cerebral blood flow (ΔCBF) and volume (…

MRI measurement of the BOLD-specific flow–volume relationship during hypercapnia and hypocapnia in humans

JJ Chen, GB Pike - Neuroimage, 2010 - Elsevier
It is widely assumed in fMRI that the relationship between cerebral blood flow (CBF) and
volume (CBV) changes observed during end-tidal CO 2 (PETCO 2 ) perturbations is equivalent …

Mapping the end-tidal CO2 response function in the resting-state BOLD fMRI signal: Spatial specificity, test–retest reliability and effect of fMRI sampling rate

…, C Chang, JB Kwinta, YB Khatamian, JJ Chen - Neuroimage, 2015 - Elsevier
The blood oxygenation level dependent (BOLD) signal measures brain function indirectly
through physiological processes and hence is susceptible to global physiological changes. …

[HTML][HTML] Effects of post-acute COVID-19 syndrome on the functional brain networks of non-hospitalized individuals

NW Churchill, E Roudaia, JJ Chen, A Gilboa… - Frontiers in …, 2023 - frontiersin.org
Introduction The long-term impact of COVID-19 on brain function remains poorly understood,
despite growing concern surrounding post-acute COVID-19 syndrome (PACS). The goal of …

[HTML][HTML] The effect of low-frequency physiological correction on the reproducibility and specificity of resting-state fMRI metrics: functional connectivity, ALFF, and ReHo

…, JB Kwinta, YB Khatamian, JJ Chen - Frontiers in …, 2017 - frontiersin.org
The resting-state fMRI (rs-fMRI) signal is affected by a variety of low-frequency physiological
phenomena, including variations in cardiac-rate (CRV), respiratory-volume (RVT), and end-…

Determinants of capital structure of Chinese-listed companies

JJ Chen - Journal of Business research, 2004 - Elsevier
This paper develops a preliminary study to explore the determinants of capital structure of
Chinese-listed companies using firm-level panel data. The findings reflect the transitional …

[HTML][HTML] A functional connectome of Parkinson's disease patients prior to deep brain stimulation: a tool for disease-specific connectivity analyses

…, R Gramer, M Paff, A Horn, JJ Chen… - Frontiers in …, 2022 - frontiersin.org
A wide range of disorders are thought to arise from dysfunction in brain circuitry (Bonelli and
Cummings, 2007). These pathological circuits are not directly appreciated on routinely …

Analysis of efficacy of functional appliances on mandibular growth

JY Chen, LA Will, R Niederman - American Journal of Orthodontics and …, 2002 - Elsevier
The purpose of this study was to examine the hypothesis that functional appliances enhance
mandibular growth in the treatment of skeletal Class II malocclusions. We systematically …