Classical benzodiazepine drugs are in wide clinical use as anxiolytics, hypnotics, anticonvulsants,
and muscle relaxants. They act by enhancing the γ-aminobutyric acid A (GABA A ) …

The neurotransmitters GABA and glycine mediate fast synaptic inhibition by activating ligand-gated
chloride channels — namely, type A GABA (GABA A ) and glycine receptors. Both …

γ-Aminobutyric acid A (GABA A ) receptors mediate most of the fast inhibitory neurotransmission
in the CNS. They represent a major site of action for clinically relevant drugs, such as …

GABA A ‐receptors display an extensive structural heterogeneity based on the differential
assembly of a family of at least 15 subunits (α1–6, β1–3, γ1–3, θ, ρl–2) into distinct …

In this Letter, the X-ray Laue patterns used to give the orientation of our crystal were
misinterpreted by 458. With the magnetic field perpendicular to the RuO2 planes, the nearest-…

Benzodiazepine tranquilizers are used in the treatment of anxiety disorders. To identify the
molecular and neuronal target mediating the anxiolytic action of benzodiazepines, we …

Most fast inhibitory neurotransmission in the brain is mediated by GABA A receptors, which
are mainly postsynaptic and consist of diverse α and ß subunits together with the γ2 subunit. …

The heterogeneity of γ-aminobutyric acid type A (GABA A ) receptors contributes to the diversity
of neuronal inhibition in the regulation of information processing. Although most GABA A …

Patients with panic disorders show a deficit of GABA A receptors in the hippocampus,
parahippocampus and orbitofrontal cortex. Synaptic clustering of GABA A receptors in mice …

The involvement of GABA in neuronal differentiation and maturation precedes its role as
inhibitory neurotransmitter in the brain. It was therefore investigated whether GABAA receptors …