Regional gray matter volume abnormalities in the at risk mental state

…, A Riecher-Rössler, P Dazzan, X Chitnis, J Aston… - Biological …, 2007 - Elsevier
BACKGROUND: Individuals with an At Risk Mental State (ARMS) have a very high risk of
developing a psychotic disorder but the basis of this risk is unclear. We addressed this issue by …

Efficacy of using cognitive status in predicting psychosis: a 7-year follow-up

A Riecher-Rössler, MO Pflueger, J Aston… - Biological …, 2009 - Elsevier
BACKGROUND: Despite extensive early detection research in schizophrenic psychoses,
methods for identifying at-risk individuals and predicting their transition to psychosis are still …

Reductions in frontal, temporal and parietal volume associated with the onset of psychosis

SJ Borgwardt, PK McGuire, J Aston… - Schizophrenia …, 2008 - Elsevier
BACKGROUND: Volumetric MRI abnormalities similar to those evident in schizophrenia are
also evident in people at very high risk of psychosis. Which volumetric abnormalities are …

Structural brain abnormalities in individuals with an at-risk mental state who later develop psychosis

SJ Borgwardt, PK McGuire, J Aston… - The British Journal of …, 2007 - cambridge.org
BackgroundNeuroanatomical abnormalities are a well-established feature of schizophrenia.
However, the timing of their emergence and the extent to which they are related to …

Help-seeking and pathways to care in the early stages of psychosis

GJ Fridgen, J Aston, U Gschwandtner… - Social psychiatry and …, 2013 - Springer
Purpose Delay in the treatment of a first psychotic episode can have a negative influence on
the future course of the disease. In this context, it is important to examine pathways to care …

Hyperprolactinaemia in early psychosis—not only due to antipsychotics

J Aston, E Rechsteiner, N Bull, S Borgwardt… - Progress in Neuro …, 2010 - Elsevier
Hyperprolactinaemia is often found in patients with schizophrenia and usually considered a
consequence of antipsychotics. Prolactin levels were measured in 43 At-Risk Mental State …

Brain connectivity abnormalities predating the onset of psychosis: correlation with the effect of medication

A Schmidt, R Smieskova, J Aston, A Simon… - JAMA …, 2013 - jamanetwork.com
Importance Brain imaging studies have identified robust changes in brain structure and function
during the development of psychosis, but the contribution of abnormal brain connectivity …

Pathologic gambling in patients with Parkinson's disease

U Gschwandtner, J Aston, S Renaud… - Clinical …, 2001 - journals.lww.com
Patients with Parkinson's disease frequently have depression, anxiety, and obsessive-compulsive
disorder. We observed two patients who had episodes of pathologic gambling. At the …

Distinguishing prodromal from first-episode psychosis using neuroanatomical single-subject pattern recognition

S Borgwardt, N Koutsouleris, J Aston… - Schizophrenia …, 2013 - academic.oup.com
Background: The at-risk mental state for psychosis (ARMS) and the first episode of
psychosis have been associated with structural brain abnormalities that could aid in the …

Hippocampus abnormalities in at risk mental states for psychosis? A cross-sectional high resolution region of interest magnetic resonance imaging study

E Buehlmann, GE Berger, J Aston… - Journal of psychiatric …, 2010 - Elsevier
BACKGROUND: Hippocampal volume (HV) reduction is well documented in schizophrenia.
However, it is still unclear whether this change is a pre-existing vulnerability factor, a sign of …