User profiles for James H. Cole
 | James H ColeProfessor of Neuroimage Computing, Centre for Medical Image Computing, Dementia … Verified email at ucl.ac.uk Cited by 10271 |
Predicting age using neuroimaging: innovative brain ageing biomarkers
The brain changes as we age and these changes are associated with functional deterioration
and neurodegenerative disease. It is vital that we better understand individual differences …
and neurodegenerative disease. It is vital that we better understand individual differences …
Predicting brain age with deep learning from raw imaging data results in a reliable and heritable biomarker
Abstract Machine learning analysis of neuroimaging data can accurately predict chronological
age in healthy people. Deviations from healthy brain ageing have been associated with …
age in healthy people. Deviations from healthy brain ageing have been associated with …
[HTML][HTML] Multimodality neuroimaging brain-age in UK biobank: relationship to biomedical, lifestyle, and cognitive factors
JH Cole - Neurobiology of aging, 2020 - Elsevier
The brain-age paradigm is proving increasingly useful for exploring aging-related disease
and can predict important future health outcomes. Most brain-age research uses structural …
and can predict important future health outcomes. Most brain-age research uses structural …
Increased brain-predicted aging in treated HIV disease
Objective: To establish whether HIV disease is associated with abnormal levels of age-related
brain atrophy, by estimating apparent brain age using neuroimaging and exploring …
brain atrophy, by estimating apparent brain age using neuroimaging and exploring …
Optical fiber sensor technology
…, A Dandridge, GH Sigel, JH Cole… - IEEE transactions on …, 1982 - ieeexplore.ieee.org
The current state of the art of optical fiber sensors is reviewed. The principles of operation
are detailed and the various types of fiber sensors are outlined. Achievable performance and …
are detailed and the various types of fiber sensors are outlined. Achievable performance and …
[HTML][HTML] Brain age predicts mortality
Age-associated disease and disability are placing a growing burden on society. However,
ageing does not affect people uniformly. Hence, markers of the underlying biological ageing …
ageing does not affect people uniformly. Hence, markers of the underlying biological ageing …
[HTML][HTML] ENIGMA and global neuroscience: A decade of large-scale studies of the brain in health and disease across more than 40 countries
…, MJ Wright, JY Yun, G Zhang, Y Zhang-James… - Translational …, 2020 - nature.com
This review summarizes the last decade of work by the ENIGMA (Enhancing NeuroImaging
Genetics through Meta Analysis) Consortium, a global alliance of over 1400 scientists across …
Genetics through Meta Analysis) Consortium, a global alliance of over 1400 scientists across …
Improved bend loss formula verified for optical fiber by simulation and experiment
RT Schermer, JH Cole - IEEE journal of quantum electronics, 2007 - ieeexplore.ieee.org
This paper presents an improved curvature loss formula for optical waveguides, which is
shown to accurately predict the bend loss of both single-mode and multimode fibers. The …
shown to accurately predict the bend loss of both single-mode and multimode fibers. The …
Prediction of brain age suggests accelerated atrophy after traumatic brain injury
Objective The long‐term effects of traumatic brain injury (TBI) can resemble observed in
normal ageing, suggesting that TBI may accelerate the ageing process. We investigate this …
normal ageing, suggesting that TBI may accelerate the ageing process. We investigate this …
[HTML][HTML] Brain age and other bodily 'ages': implications for neuropsychiatry
As our brains age, we tend to experience cognitive decline and are at greater risk of
neurodegenerative disease and dementia. Symptoms of chronic neuropsychiatric diseases are also …
neurodegenerative disease and dementia. Symptoms of chronic neuropsychiatric diseases are also …