IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with …
…, DL Kamen, GS Gilkeson, TJ Vyse, JA James… - Annals of the …, 2012 - ard.bmj.com
Objective High serum interferon α (IFNα) activity is a heritable risk factor for systemic lupus
erythematosus (SLE). Auto-antibodies found in SLE form immune complexes which can …
erythematosus (SLE). Auto-antibodies found in SLE form immune complexes which can …
Characterization of uptake of the new PET imaging compound 18F-fluorobenzyl triphenyl phosphonium in dog myocardium
…, J Hilton, L Volokh, RF Dannals, JJ Frost… - Journal of Nuclear …, 2006 - Soc Nuclear Med
18 F-Labeled p-fluorobenzyl triphenyl phosphonium cation ( 18 F-FBnTP) is a member of a
new class of positron-emitting lipophilic cations that may act as myocardial perfusion PET …
new class of positron-emitting lipophilic cations that may act as myocardial perfusion PET …
Characterization of membrane potential-dependent uptake of the novel PET tracer 18F-fluorobenzyl triphenylphosphonium cation
Purpose Mitochondrial dysfunction has been attributed a critical role in the etiology and
pathogenesis of numerous diseases, and is manifested by alterations of the organelle’s …
pathogenesis of numerous diseases, and is manifested by alterations of the organelle’s …
Mu-opioid receptor binding measured by [11C] carfentanil positron emission tomography is related to craving and mood in alcohol dependence
…, ME McCaul, YK Kim, N Ilgin, RF Dannals, JJ Frost - Biological …, 2004 - Elsevier
BACKGROUND: The endogenous opioid system has been linked to alcohol dependence
through animal and human studies. We investigated the relationship between alcohol craving …
through animal and human studies. We investigated the relationship between alcohol craving …
Naloxone increases pain induced by topical capsaicin in healthy human volunteers
WS Anderson, RN Sheth, B Bencherif, JJ Frost… - Pain, 2002 - Elsevier
Opioid receptors occur in locations of strategic importance within the central nervous system
for modulation of pain. Is pain reduced by ongoing inhibition mediated by activation of these …
for modulation of pain. Is pain reduced by ongoing inhibition mediated by activation of these …
PET imaging of human cardiac opioid receptors
…, RF Dannals, HT Ravert, JJ Frost - European journal of …, 2002 - Springer
The presence of opioid peptides and receptors and their role in the regulation of cardiovascular
function has been previously demonstrated in the mammalian heart. The aim of this …
function has been previously demonstrated in the mammalian heart. The aim of this …
Imaging δ-and μ-opioid receptors by PET in lung carcinoma patients
…, J Brahmer, H Ravert, R Dannals, JJ Frost - Journal of Nuclear …, 2007 - Soc Nuclear Med
In the present study, we measured the kinetics and distribution in vivo of the selective δ-opioid
antagonist 11 C-methylnaltrindole ( 11 C-MeNTI) and the μ-opioid agonist 11 C-…
antagonist 11 C-methylnaltrindole ( 11 C-MeNTI) and the μ-opioid agonist 11 C-…
Application of MRI-based partial-volume correction to the analysis of PET images of μ-opioid receptors using statistical parametric mapping
…, MJ Stumpf, JM Links, JJ Frost - Journal of Nuclear …, 2004 - Soc Nuclear Med
The accurate quantification of brain radioactivity concentration is limited by the spatial resolution
of the PET scanner for structures smaller than 2–3 times the resolution. In the presence …
of the PET scanner for structures smaller than 2–3 times the resolution. In the presence …
High-resolution imaging of brain 5-HT1B receptors in the rhesus monkey using [11C] P943
…, Y Huang, D Weinzimmer, J Ropchan, JJ Frost… - Nuclear medicine and …, 2010 - Elsevier
The serotonin 5-HT 1B receptors regulate the release of serotonin and are involved in
various disease states, including depression and schizophrenia. The goal of the study was to …
various disease states, including depression and schizophrenia. The goal of the study was to …
Receptor imaging by positron emission tomography and single-photon emission computed tomography
JJ FROST - Investigative radiology, 1992 - journals.lww.com
… JAMES FROST, MD, PD Frost JJ Receptor imaging by positron emission tomography
and single-photon emission computed tomography. Invest Radiol 1992; 27:S54–S58 …
and single-photon emission computed tomography. Invest Radiol 1992; 27:S54–S58 …