OBJECTIVE Hyperbaric oxygen therapy (HBOT) is used for the treatment of chronic diabetic
foot ulcers (DFUs). The controlled evidence for the efficacy of this treatment is limited. The …

Objectives The objective of the study is to present the Grading of Recommendations
Assessment, Development, and Evaluation (GRADE) conceptual approach to the assessment of …

Background: Approximately 35% of people with depression do not respond to 2 courses of
antidepressant medications of adequate dosage, and treatment-resistant depression (TRD) is …

Study objective To present a review of out-of-hospital identification of ST-segment elevation
myocardial infarction patients transported by emergency medical services with 12-lead ECG …

The pharmacological treatment of depression consists of stages of trial and error, with less
than 40% of patients achieving remission during first medication trial. However, in a large, …

… A Chambers and JM Bowen … Chambers A, Bowen JM. Electrical stimulation for drug-resistant
epilepsy: an evidence-based analysis. Ont Health Technol Assess Ser [Internet]. … Bowen …

The purpose of this book is to introduce the phosphorus (P) removal structure as a new BMP
for reducing dissolved P loading to surface waters from non-point source pollution, provide …

Background In August 2011 a proposed epilepsy care model was presented to the Ontario
Health Technology Advisory Committee (OHTAC) by an Expert Panel on a Provincial Strategy …

Objective Little is known about the burden of osteoarthritis (OA) in Canada. This study was
undertaken to estimate the excess burden of OA in Ontario, the largest province in Canada. …

Objectives: Approximately 10–15 percent of individuals with diabetes mellitus develop foot
ulcers, which precede 85 percent of amputations. Increased oxygen, through the use of …