The long-term health effects of physical, sexual, and emotional abuse during childhood were
studied in a sample of 668 middle class females in a gynecologic practice who responded …

Background Regional cerebral blood flow (CBF), a good indirect index of cerebral pathologic
changes in Alzheimer disease (AD), is more severely reduced in patients with higher …

Early‐onset idiopathic torsion dystonia (ITD) is an autosomal dominant hyperkinetic movement
disorder with incomplete penetrance, associated with a 3 base‐pair deletion in the DYT1 …

OBJECTIVE: To evaluate the clinical course and predictors of outcome in outpatients with
cognitive impairment who do not meet criteria for dementia at initial evaluation. DESIGN: …

Background: Global and regional deficits in cerebral blood flow and glucose metabolism
have been reported in major depression, but there is limited information on the effects of …

Background: The efficacy of electroconvulsive therapy (ECT) is determined by stimulus
electrical intensity and electrode placement. Three theories offer different accounts for why …

The identification of discrete patterns of altered functional brain circuitry in preclinical
Huntington’s disease (HD) gene carriers is important to understanding the pathophysiology of this …

Recent advances in functional neuroimaging have presented a challenge to traditional
statistical methods in characterizing the effects of neuropsychiatric illness on brain function. The …

• We measured regional cerebral blood flow with the xenon 133 inhalation technique in 41
patients with major depressive disorder and 40 matched, normal controls during an eyes-…

Healthy aging is associated with brain volume reductions that involve the frontal cortex, but
also affect other brain regions. We sought to identify an age-related network pattern of MRI …