User profiles for Jeffrey Meyer

Jeffrey Meyer

Verified email at camhpet.ca
Cited by 18305

Nifedipine: dose-related increase in mortality in patients with coronary heart disease

CD Furberg, BM Psaty, JV Meyer - Circulation, 1995 - Am Heart Assoc
Background The purpose of this study was to assess the effect of the dose of nifedipine, a
dihydropyridine calcium antagonist, on the increased risk of mortality seen in the randomized …

Role of translocator protein density, a marker of neuroinflammation, in the brain during major depressive episodes

…, JL Kennedy, PV Rekkas, S Houle, JH Meyer - JAMA …, 2015 - jamanetwork.com
Importance The neuroinflammatory hypothesis of major depressive disorder is supported by
several main findings. First, in humans and animals, activation of the immune system …

Changes in regional brain glucose metabolism measured with positron emission tomography after paroxetine treatment of major depression

…, S Krüger, HS Mayberg, JH Meyer… - American Journal of …, 2001 - Am Psychiatric Assoc
OBJECTIVE: Depression is commonly associated with frontal hypometabolic activity
accompanied by hypermetabolism in certain limbic regions. It is unclear whether successful …

Elevated monoamine oxidase a levels in the brain: an explanation for the monoamine imbalance of major depression

JH Meyer, N Ginovart, A Boovariwala… - Archives of general …, 2006 - jamanetwork.com
Context The monoamine theory of depression proposes that monoamine levels are lowered,
but there is no explanation for how monoamine loss occurs. Monoamine oxidase A (MAO-A…

The linear-quadratic model is inappropriate to model high dose per fraction effects in radiosurgery

JP Kirkpatrick, JJ Meyer, LB Marks - Seminars in radiation oncology, 2008 - Elsevier
The linear-quadratic (LQ) model is widely used to model the effect of total dose and dose per
fraction in conventionally fractionated radiotherapy. Much of the data used to generate the …

Serotonin Transporter Occupancy of Five Selective Serotonin Reuptake Inhibitors at Different Doses: An [11C]DASB Positron Emission Tomography Study

JH Meyer, AA Wilson, S Sagrati… - American Journal of …, 2004 - Am Psychiatric Assoc
OBJECTIVE: Minimum therapeutic doses of paroxetine and citalopram produce 80%
occupancy for the serotonin (5-HT) transporter (5-HTT). The authors used [ 11 C]DASB positron …

Smoking-induced ventral striatum dopamine release

…, ED London, J Farahi, JH Meyer… - American Journal of …, 2004 - Am Psychiatric Assoc
OBJECTIVE: Substantial evidence from animal models demonstrates that dopamine release
in the ventral striatum underlies the reinforcing properties of nicotine. The authors used [ 11 …

Occupancy of Serotonin Transporters by Paroxetine and Citalopram During Treatment of Depression: A [11C]DASB PET Imaging Study

JH Meyer, AA Wilson, N Ginovart… - American Journal of …, 2001 - Am Psychiatric Assoc
OBJECTIVE: Selective serotonin reuptake inhibitors are commonly used to treat major
depression; however, the percentage of serotonin (5-HT) transporter (5-HTT) sites occupied …

Lower dopamine transporter binding potential in striatum during depression

JH Meyer, S Krüger, AA Wilson, BK Christensen… - …, 2001 - journals.lww.com
Previous studies suggest that there is a dopamine lowering process during major depressive
episodes (MDE). To investigate this, we measured the dopamine transporter binding …

Imaging the serotonin transporter during major depressive disorder and antidepressant treatment: 2005 CCNP Young Investigator Award Paper

JH Meyer - Journal of Psychiatry and Neuroscience, 2007 - jpn.ca
This paper focuses on serotonin transporter 5-HTT imaging to investigate major depressive
disorder (MDD) and antidepressant occupancy. Such investigations have only recently been …