The clinical use of deep brain stimulation (DBS) is among the most important advances in
the clinical neurosciences in the past two decades. As a surgical tool, DBS can directly …

Deep brain stimulation (DBS) is a neurosurgical procedure that allows targeted circuit-based
neuromodulation. DBS is a standard of care in Parkinson disease, essential tremor and …

Objective: To investigate the long-term efficacy and adverse cognitive effects of stereotactic
bilateral anterior cingulotomy as a treatment for refractory obsessive-compulsive disorder (…

Background For patients with psychiatric illnesses remaining refractory to ‘standard’ therapies,
neurosurgical procedures may be considered. Guidelines for safe and ethical conduct of …

Background Several options exist for surgical management of essential tremor (ET), including
radiofrequency lesioning, deep brain stimulation and γ knife radiosurgery of the ventralis …

We developed a method for the efficient generation of functional dopaminergic (DA) neurons
from human embryonic stem cells (hESCs) on a large scale. The most unique feature of this …

Background Unilateral focused ultrasound ablation of the internal segment of globus pallidus
has reduced motor symptoms of Parkinson’s disease in open-label studies. Methods We …

Kyungsik Eom, Jinhyung Kim, Jong Min Choi, Taekyeong Kang, Jin Woo Chang, Kyung Min
Byun,* Sang Beom Jun,* and Sung June Kim* direct optical path and be utilized to improve …

OBJECT Magnetic resonance-guided focused ultrasound surgery (MRgFUS) was recently
introduced as treatment for movement disorders such as essential tremor and advanced …

Object Whole-brain radiation therapy (WBRT), open resection, and stereotactic radiosurgery
(SRS) are widely used for treatment of metastatic brain lesions, and many physicians …