User profiles for Joanne Ryan
Joanne RyanMonash University Verified email at monash.edu Cited by 9248 |
[HTML][HTML] Effect of aspirin on cardiovascular events and bleeding in the healthy elderly
Background Aspirin is a well-established therapy for the secondary prevention of cardiovascular
events. However, its role in the primary prevention of cardiovascular disease is unclear, …
events. However, its role in the primary prevention of cardiovascular disease is unclear, …
[HTML][HTML] Effect of aspirin on all-cause mortality in the healthy elderly
Background In the primary analysis of the Aspirin in Reducing Events in the Elderly (ASPREE)
trial, now published in the Journal, we report that the daily use of aspirin did not provide a …
trial, now published in the Journal, we report that the daily use of aspirin did not provide a …
[HTML][HTML] Effect of aspirin on disability-free survival in the healthy elderly
Background Information on the use of aspirin to increase healthy independent life span in
older persons is limited. Whether 5 years of daily low-dose aspirin therapy would extend …
older persons is limited. Whether 5 years of daily low-dose aspirin therapy would extend …
[HTML][HTML] The epigenetic clock as a predictor of disease and mortality risk: a systematic review and meta-analysis
Background Ageing is one of the principal risk factors for many chronic diseases. However,
there is considerable between-person variation in the rate of ageing and individual …
there is considerable between-person variation in the rate of ageing and individual …
[HTML][HTML] Social isolation, social support and loneliness as predictors of cardiovascular disease incidence and mortality
Background Poor social health is associated with increased risk of cardiovascular disease (CVD).
Recent research suggests that different social health domains should be considered …
Recent research suggests that different social health domains should be considered …
[HTML][HTML] Quality of life and mortality in the general population: a systematic review and meta-analysis
Background Quality of life (QoL) is multi-dimensional concept of an individual’ general well-being
status in relation to their value, environment, cultural and social context in which they …
status in relation to their value, environment, cultural and social context in which they …
Postnatal stability, tissue, and time specific effects of AHRR methylation change in response to maternal smoking in pregnancy
The intrauterine environment has the potential to “program” the developing fetus in a way
that can be potentially deleterious to later health. While in utero environmental/stochastic …
that can be potentially deleterious to later health. While in utero environmental/stochastic …
Epigenetics and depressive disorders: a review of current progress and future directions
Background: Several broad lines of evidence support the involvement of epigenetic processes
in neurodevelopment and psychiatric disorders. Epigenetic disruption also provides a …
in neurodevelopment and psychiatric disorders. Epigenetic disruption also provides a …
Randomized placebo-controlled trial of the effects of aspirin on dementia and cognitive decline
Objective To determine the effect of low-dose aspirin vs placebo on incident all-cause dementia,
incident Alzheimer disease (AD), mild cognitive impairment (MCI), and cognitive decline …
incident Alzheimer disease (AD), mild cognitive impairment (MCI), and cognitive decline …
[HTML][HTML] BDNF promoter methylation and genetic variation in late-life depression
The regulation of the brain-derived neurotrophic factor (BDNF) is important for depression
pathophysiology and epigenetic regulation of the BDNF gene may be involved. This study …
pathophysiology and epigenetic regulation of the BDNF gene may be involved. This study …