User profiles for Joel Ramirez

Joel Ramirez

Sunnybrook
Verified email at sri.utoronto.ca
Cited by 5748

Perivascular spaces in the brain: anatomy, physiology and pathology

…, H Lee, FN Doubal, R Brown, J Ramirez… - Nature Reviews …, 2020 - nature.com
Perivascular spaces include a variety of passageways around arterioles, capillaries and
venules in the brain, along which a range of substances can move. Although perivascular …

Vascular dysfunction—the disregarded partner of Alzheimer's disease

…, DJJ Wang, RE Jacobs, FN Doubal, J Ramirez… - Alzheimer's & …, 2019 - Elsevier
Increasing evidence recognizes Alzheimer's disease (AD) as a multifactorial and heterogeneous
disease with multiple contributors to its pathophysiology, including vascular dysfunction…

Retrieval of autobiographical memory in Alzheimer's disease: relation to volumes of medial temporal lobe and other structures

A Gilboa, J Ramirez, S Köhler, R Westmacott… - …, 2005 - Wiley Online Library
The representation of autobiographical memory is distributed over a network of brain
structures, with the medial temporal lobe (MTL) at its epicenter. Some believe that, over time, all …

Hippocampal segmentation for brains with extensive atrophy using three‐dimensional convolutional neural networks

…, EE Ntiri, H Akhavein, M Holmes, S Nestor, J Ramirez… - 2020 - Wiley Online Library
Hippocampal volumetry is a critical biomarker of aging and dementia, and it is widely used
as a predictor of cognitive performance; however, automated hippocampal segmentation …

Visible Virchow-Robin spaces on magnetic resonance imaging of Alzheimer's disease patients and normal elderly from the Sunnybrook Dementia Study

J Ramirez, C Berezuk, AA McNeely… - Journal of …, 2015 - content.iospress.com
Background: Visible Virchow-Robin spaces (VRS) are commonly used markers for small
vessel disease in aging and dementia. Objective: However, as previous reports were based on …

Imaging the perivascular space as a potential biomarker of neurovascular and neurodegenerative diseases

J Ramirez, C Berezuk, AA McNeely, F Gao… - Cellular and molecular …, 2016 - Springer
Although the brain lacks conventional lymphatic vessels found in peripheral tissue, evidence
suggests that the space surrounding the vasculature serves a similar role in the clearance …

Lesion Explorer: a comprehensive segmentation and parcellation package to obtain regional volumetrics for subcortical hyperintensities and intracranial tissue

J Ramirez, E Gibson, A Quddus, NJ Lobaugh… - Neuroimage, 2011 - Elsevier
Subcortical hyperintensities (SH) are a commonly observed phenomenon on MRI of the
aging brain (Kertesz et al., 1988). Conflicting behavioral, cognitive and pathological …

[HTML][HTML] Perivascular spaces segmentation in brain MRI using optimal 3D filtering

…, R Lovreglio, MC Valdés Hernández, J Ramirez… - Scientific reports, 2018 - nature.com
Perivascular Spaces (PVS) are a feature of Small Vessel Disease (SVD), and are an important
part of the brain’s circulation and glymphatic drainage system. Quantitative analysis of …

Associations between amyloid β and white matter hyperintensities: a systematic review

A Roseborough, J Ramirez, SE Black… - Alzheimer's & Dementia, 2017 - Elsevier
Introduction This systematic review synthesizes current evidence for associations between
cortical amyloid β, visualized on amyloid positron emission tomography imaging, and white …

The Canadian dementia imaging protocol: harmonizing national cohorts

…, R Hoge, CR McCreary, J Ramirez… - Journal of Magnetic …, 2019 - Wiley Online Library
Background Harmonized protocols to collect imaging data must be devised, employed, and
maintained in multicentric studies to reduce interscanner variability in subsequent analyses. …