Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication
B Chen, D Dowlatshahi, GM MacQueen, JF Wang… - Biological …, 2001 - Elsevier
Background: The cAMP signaling pathway, and its downstream neurotrophic factor BDNF,
are major targets of antidepressant medications. Abnormalities in this pathway have …
are major targets of antidepressant medications. Abnormalities in this pathway have …
Synthesis of Copper Peroxide Nanodots for H2O2 Self-Supplying Chemodynamic Therapy
Chemodynamic therapy (CDT) employs Fenton catalysts to kill cancer cells by converting
intracellular H 2 O 2 into hydroxyl radical (•OH), but endogenous H 2 O 2 is insufficient to …
intracellular H 2 O 2 into hydroxyl radical (•OH), but endogenous H 2 O 2 is insufficient to …
Decreased levels of glutathione, the major brain antioxidant, in post-mortem prefrontal cortex from patients with psychiatric disorders
JW Gawryluk, JF Wang, AC Andreazza… - International Journal …, 2011 - academic.oup.com
Accruing data suggest that oxidative stress may be a factor underlying the pathophysiology
of bipolar disorder (BD), major depressive disorder (MDD), and schizophrenia (SCZ). …
of bipolar disorder (BD), major depressive disorder (MDD), and schizophrenia (SCZ). …
Mitochondrial complex I activity and oxidative damage to mitochondrial proteins in the prefrontal cortex of patients with bipolar disorder
AC Andreazza, L Shao, JF Wang… - Archives of general …, 2010 - jamanetwork.com
Context Accumulating evidence suggests that mitochondrial dysfunction and oxidative stress
contribute to the pathogenesis of bipolar disorder and schizophrenia. It remains unclear …
contribute to the pathogenesis of bipolar disorder and schizophrenia. It remains unclear …
Increased temporal cortex CREB concentrations and antidepressant treatment in major depression
Blunted brain cyclic adenosine monophosphate (cAMP) signalling is purported to occur in
major depressive disorder (MDD). 1 Furthermore, antidepressants increase concentrations of …
major depressive disorder (MDD). 1 Furthermore, antidepressants increase concentrations of …
Direct observation of high-temperature superconductivity in one-unit-cell FeSe films
…, JF Wang, ZC Xia, L Li, YY Wang, J Wang… - Chinese Physics …, 2014 - iopscience.iop.org
We prepared one-unit-cell (1-UC) thick FeSe films on insulating SrTiO 3 substrates with non-superconducting
FeTe protection layers by molecular beam epitaxy for ex situ studies. By …
FeTe protection layers by molecular beam epitaxy for ex situ studies. By …
Increased oxidative stress in the anterior cingulate cortex of subjects with bipolar disorder and schizophrenia
JF Wang, L Shao, X Sun, LT Young - Bipolar disorders, 2009 - Wiley Online Library
Background: Recent studies indicate the presence of mitochondrial dysfunction in brains of
subjects with bipolar disorder (BD). Because the mitochondrial electron transport chain is a …
subjects with bipolar disorder (BD). Because the mitochondrial electron transport chain is a …
Downregulation in components of the mitochondrial electron transport chain in the postmortem frontal cortex of subjects with bipolar disorder
X Sun, JF Wang, M Tseng, LT Young - Journal of Psychiatry and …, 2006 - jpn.ca
Objective: Many studies indicate a genetic predisposition to bipolar disorder (BD) and suggest
that a number of abnormal genes are involved in its development. In this study, we used …
that a number of abnormal genes are involved in its development. In this study, we used …
[PDF][PDF] Single-cell characterization of malignant phenotypes and developmental trajectories of adrenal neuroblastoma
…, XY Yao, WQ Luo, XM Cheng, JJ Miao, JF Wang… - Cancer Cell, 2020 - cell.com
Neuroblastoma (NB), which is a subtype of neural-crest-derived malignancy, is the most
common extracranial solid tumor occurring in childhood. Despite extensive research, the …
common extracranial solid tumor occurring in childhood. Despite extensive research, the …
Chronic treatment with mood stabilizers lithium and valproate prevents excitotoxicity by inhibiting oxidative stress in rat cerebral cortical cells
L Shao, LT Young, JF Wang - Biological psychiatry, 2005 - Elsevier
BACKGROUND: Recent studies indicate that chronic treatment with the mood-stabilizing drugs
lithium and valproate produces a neuroprotective effect against excitotoxicity. In this study…
lithium and valproate produces a neuroprotective effect against excitotoxicity. In this study…
