In functional magnetic resonance imaging (fMRI) research one is typically interested in neural
activity. However, the blood‐oxygenation level‐dependent (BOLD) signal is a composite …

The maintenance of wellbeing across the lifespan depends on the preservation of cognitive
function. We propose that successful cognitive aging is determined by interactions both …

… The details of this procedure, including methods of outlier detection are described in Tsvetanov
et al. [2015]. LF and HF-HRV were log-transformed to obtain more normal distributions. …

Neuroinflammation is a key part of the etio-pathogenesis of Alzheimer's disease (AD). We
tested the relationship between neuroinflammation and the disruption of functional …

Ageing is commonly associated with changes to segregation and integration of functional
brain networks, but, in isolation, current network-based approaches struggle to elucidate …

Tau pathology, neuroinflammation, and neurodegeneration are key aspects of Alzheimer’s
disease. Understanding whether these features predict cognitive decline, alone or in …

The syndromes caused by frontotemporal lobar degeneration have highly heterogeneous
and overlapping clinical features. There has been great progress in the refinement of clinical …

The locus coeruleus (LC), the origin of noradrenergic modulation of cognitive and behavioral
function, may play an important role healthy ageing and in neurodegenerative conditions. …

The control of voluntary movement changes markedly with age. A critical component of motor
control is the integration of sensory information with predictions of the consequences of …

Much is known about how age affects the brain during tightly controlled, though largely contrived,
experiments, but do these effects extrapolate to everyday life? Naturalistic stimuli, such …