Neonatal rat microglia derived from different brain regions have distinct activation responses
AY Lai, KS Dhami, CD Dibal, KG Todd - Neuron glia biology, 2011 - cambridge.org
The regional heterogeneity of neuronal phenotypes is a well-known phenomenon. Whether
or not glia derived from different brain regions are phenotypically and functionally distinct is …
or not glia derived from different brain regions are phenotypically and functionally distinct is …
Differential expression of PKC isoforms in developing zebrafish
SA Patten, RK Sihra, KS Dhami, CA Coutts… - International journal of …, 2007 - Elsevier
Protein kinase C isozymes are a biologically diverse group of enzymes known to be involved
in a wide variety of cellular processes. They fall into three families (conventional, novel and …
in a wide variety of cellular processes. They fall into three families (conventional, novel and …
Fluoxetine and its metabolite norfluoxetine induce microglial apoptosis
KS Dhami, MA Churchward, GB Baker… - Journal of …, 2019 - Wiley Online Library
Inflammatory insult to the central nervous system ( CNS ) can lead to development of
depression, and subsequently depression is the most frequent psychiatric comorbidity following …
depression, and subsequently depression is the most frequent psychiatric comorbidity following …
Moving past the “neuroncentric” perspective: a role for glia in neuropsychiatric disorders
AY Lai, KS Dhami, KG Todd - Journal of Psychiatry and Neuroscience, 2009 - jpn.ca
The development of neuropsychiatric disorders involves an array of different underlying
mechanisms, many of which remain at the level of hypotheses and thus the centre of much …
mechanisms, many of which remain at the level of hypotheses and thus the centre of much …
Inducing Ubiquitylation and Protein Degradation as a Drug Development Strategy
KS Dhami, XD Huang - Targeted Protein Degradation: Methods and …, 2021 - Springer
A new drug discovery strategy by inducing the degradation of oncoproteins through ubiquitin–proteasome
system (UPS) has gained a lot of traction in the last decade (Verma et al. Mol …
system (UPS) has gained a lot of traction in the last decade (Verma et al. Mol …
[BOOK][B] The effects of antidepressants on the phenotype of activated microglia and ischemia-injured cortical neurons
KS Dhami - 2013 - search.proquest.com
… The first scientist to provide support of Hortega’s claims was … just as important to know what
is going on in a man’s head as … Parkinson’s and Alzheimer’s disease and acute insults such …
is going on in a man’s head as … Parkinson’s and Alzheimer’s disease and acute insults such …
ANTIDEPRESSANT DRUGS ALTER THE PHENOTYPE OF ACTIVATED MICROGLIA THEREBY AFFECTING NEURONAL FATE
K Dhami, CD Dibal, KG Todd - GLIA, 2009 - researchgate.net
… Kamaldeep S Dhami … Kamaldeep Dhami … Kamaldeep Dhami …
Kinase-deficient BTK mutants confer ibrutinib resistance through activation of the kinase HCK
K Dhami, A Chakraborty, TL Gururaja, LWK Cheung… - Science …, 2022 - science.org
… for 50 s (at 2-s intervals). Stimulant [anti-chicken IgM (10 μg/ml; SouthernBiotech, 8300-01)]
was then added, and calcium flux was immediately measured for 200 s at 2-s intervals. …
was then added, and calcium flux was immediately measured for 200 s at 2-s intervals. …
Anti-inflammatory role of GM1 and other gangliosides on microglia
…, N Steinberg, A Zaidi, G Shrivastava, K Dhami… - Journal of …, 2022 - Springer
Background Gangliosides are glycosphingolipids highly enriched in the brain, with important
roles in cell signaling, cell-to-cell communication, and immunomodulation. Genetic defects …
roles in cell signaling, cell-to-cell communication, and immunomodulation. Genetic defects …
Novel targets for development of drugs for treating schizophrenia: focus on glycine, D-serine and nitric oxide
K Dhami, M MacKay, JP Maia-de-Oliveira… - … Bülteni-Bulletin of …, 2013 - Taylor & Francis
… Consistent with the involvement of dopamine in cognitive processes governed by the
prefrontal cortex, SSR504734’s effect of enhancing frontal dopaminergic neurotransmission may …
prefrontal cortex, SSR504734’s effect of enhancing frontal dopaminergic neurotransmission may …