[HTML][HTML] Lipid droplets: a dynamic organelle moves into focus

M Beller, K Thiel, PJ Thul, H Jäckle - FEBS letters, 2010 - Elsevier
Lipid droplets (LDs) were perceived as static storage deposits, which passively participate
in the energy homeostasis of both cells and entire organisms. However, this view has …

[PDF][PDF] Lipid droplets control the maternal histone supply of Drosophila embryos

Z Li, K Thiel, PJ Thul, M Beller, RP Kühnlein, MA Welte - Current Biology, 2012 - cell.com
Background Histones are essential for chromatin packing, yet free histones not incorporated
into chromatin are toxic. While in most cells multiple regulatory mechanisms prevent …

[HTML][HTML] Reduced hippocampal gray matter volume is a common feature of patients with major depression, bipolar disorder, and schizophrenia spectrum disorders

…, H Lemke, S Meinert, A Winter, F Breuer, K Thiel… - Molecular …, 2022 - nature.com
Major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia spectrum disorder
(SSD, schizophrenia, and schizoaffective disorder) overlap in symptomatology, risk factors…

Psychopathological syndromes across affective and psychotic disorders correlate with gray matter volumes

…, K Ringwald, JK Pfarr, S Meinert, K Thiel… - Schizophrenia …, 2021 - academic.oup.com
Introduction More than a century of research on the neurobiological underpinnings of major
psychiatric disorders (major depressive disorder [MDD], bipolar disorder [BD], schizophrenia …

[HTML][HTML] Association between body mass index and subcortical brain volumes in bipolar disorders–ENIGMA study in 2735 individuals

…, K Sim, DJ Stein, F Stein, HS Temmingh, K Thiel… - Molecular …, 2021 - nature.com
Individuals with bipolar disorders (BD) frequently suffer from obesity, which is often associated
with neurostructural alterations. Yet, the effects of obesity on brain structure in BD are …

Shared and specific patterns of structural brain connectivity across affective and psychotic disorders

…, T Borgers, M Klug, H Lemke, L Waltemate, K Thiel… - Biological …, 2023 - Elsevier
Background Altered brain structural connectivity has been implicated in the pathophysiology
of psychiatric disorders including schizophrenia (SZ), bipolar disorder (BD), and major …

Dimensions of formal thought disorder and their relation to gray-and white matter brain structure in affective and psychotic disorders

…, S Meinert, EJ Leehr, H Lemke, K Thiel… - Schizophrenia …, 2022 - academic.oup.com
Factorial dimensions and neurobiological underpinnings of formal thought disorders (FTD)
have been extensively investigated in schizophrenia spectrum disorders (SSD). However, …

[HTML][HTML] The neural signature of psychomotor disturbance in depression

…, F Stein, B Straube, L Teutenberg, K Thiel… - Molecular …, 2023 - nature.com
Up to 70% of patients with major depressive disorder present with psychomotor disturbance
(PmD), but at the present time understanding of its pathophysiology is limited. In this study, …

Association of disease course and brain structural alterations in major depressive disorder

…, R Redlich, K Dohm, EJ Leehr, K Thiel… - Depression and …, 2022 - Wiley Online Library
Introduction The investigation of disease course‐associated brain structural alterations in
Major Depressive Disorder (MDD) have resulted in heterogeneous findings, possibly due to …

Temporal stability and state-dependence of retrospective self-reports of childhood maltreatment in healthy and depressed adults.

…, R Redlich, L Waltemate, H Lemke, K Thiel… - Psychological …, 2023 - psycnet.apa.org
Retrospective self-reports of childhood maltreatment (CM) are widely used. However, their
validity has been questioned due to potential depressive bias. Yet, investigations of this …