Isolated systolic hypertension is predominantly observed in the elderly because of increased
arterial stiffness. Aggressive treatment leads to excessive lowering of diastolic blood …

Epidemiological and genome-wide association studies of severe psychiatric disorders such
as schizophrenia (SZ) and bipolar disorder (BD), suggest complex interactions between …

Importance Tractography studies investigating white matter (WM) abnormalities in patients
with bipolar disorder have yielded heterogeneous results owing to small sample sizes. The …

Patients affected by bipolar disorder (BD) frequently report abnormalities in sleep/wake
cycles. In addition, they showed abnormal oscillating melatonin secretion, a key regulator of …

Objective There is growing evidence that cerebellum plays a crucial role in cognition and
emotional regulation. Cerebellum is likely to be involved in the physiopathology of both bipolar …

Background: Previous studies have reported MRI abnormalities of the corpus callosum (CC)
in patients with bipolar disorder (BD), although only a few studies have directly compared …

… Lajnef a b c , Rémi Gadel a b c , Philippe Le Corvoisier f , Marine Delavest d e , Soufiane
Carde a b c … We thank the Clinical Investigation Centre (Katia Le Dudal) and the Plateforme de …

Exacerbation triggered by respiratory infection is an important cause of morbidity and
mortality in chronic obstructive pulmonary disease (COPD) patients. Strategies aiming to …

… 3Service de Médecine Gériatrique, HOˆpital Charles Richet, AP-HP, Villiers-Le-Bel, France
… The authors wish to thank Ms Katia Le Dudal for her technical assistance, and ‘GPH CV’ …

Background Data are available on short- and intermediate-term mortality rates after
discharge for acutely decompensated heart failure (ADHF). However, few studies specifically …