CD4 + CD25 + T cells have been identified as a population of immunoregulatory T cells,
which mediate suppression of CD4 + CD25 − T cells by cell–cell contact and not secretion of …

In previous studies, we have shown that murine CD4+ CD25+ regulatory T cells produce
high levels of TGF-β1 in a cell surface and/or secreted form, and blockade of such TGF-β1 by …

Context A growing body of evidence suggests that aberrant immunologic systems underlie
the pathophysiologic characteristics of autism spectrum disorder (ASD). However, to our …

Background There have been few epidemiological studies on gastroenteropancreatic
neuroendocrine tumors (GEP-NETs) in Japan. Methods We examined the epidemiology of GEP-…

Background Although neuroendocrine tumors (NETs) are rare, the number of patients with
NET is increasing. However, in Japan, there have been no epidemiological studies on NET …

Methamphetamine is a popular addictive drug whose use is associated with multiple
neuropsychiatric adverse events and toxic to the dopaminergic and serotonergic systems of the …

Context Autism is a neurodevelopmental disorder that is characterized by repetitive and/or
obsessive interests and behavior and by deficits in sociability and communication. Although …

Interleukin (IL)-10 and transforming growth factor (TGF)-β1 are suppressor cytokines that
frequently occur together during a regulatory T cell response. Here we used a one gene …

Context In animals, methamphetamine is known to have a neurotoxic effect on serotonin
neurons, which have been implicated in the regulation of mood, anxiety, and aggression. It …

OBJECTIVE: The authors examined dopamine transporter density in the orbitofrontal cortex,
dorsolateral prefrontal cortex, and amygdala in methamphetamine users and assessed the …