User profiles for Kerrie D. Pierce
 | Kerrie D. PierceNeuroscience Research Australia Verified email at neura.edu.au Cited by 2318 |
[HTML][HTML] Identification of intracellular and extracellular domains mediating signal transduction in the inhibitory glycine receptor chloride channel
Fast synaptic neurotransmission is mediated by transmitter-activated conformational changes
in ligand-gated ion channel receptors, culminating in opening of the integral ion channel …
in ligand-gated ion channel receptors, culminating in opening of the integral ion channel …
Molecular cloning and expression of an adenosine A2b receptor from human brain
KD Pierce, TJ Furlong, LA Selbie, J Shine - Biochemical and biophysical …, 1992 - Elsevier
A novel receptor cDNA was isolated from a human hippocampal cDNA library. The encoded
polypeptide contains structural features consistent with its classification as a G protein-…
polypeptide contains structural features consistent with its classification as a G protein-…
Mutations in SLC20A2 are a major cause of familial idiopathic basal ganglia calcification
Familial idiopathic basal ganglia calcification (IBGC) or Fahr's disease is a rare neurodegenerative
disorder characterized by calcium deposits in the basal ganglia and other brain …
disorder characterized by calcium deposits in the basal ganglia and other brain …
Preliminary evidence of the short allele of the serotonin transporter gene predicting poor response to cognitive behavior therapy in posttraumatic stress disorder
…, LP Benito, C Dobson-Stone, KD Pierce… - Biological …, 2010 - Elsevier
OBJECTIVE: This study was intended to assess the extent to which the low-expression alleles
of the serotonin transporter gene promoter predict poor response to cognitive behavior …
of the serotonin transporter gene promoter predict poor response to cognitive behavior …
Molecular characterization of a human brain adenosine A2 receptor
TJ Furlong, KD Pierce, LA Selbie, J Shine - Molecular brain research, 1992 - Elsevier
A cDNA encoding a G protein-coupled receptor of unknown ligand specificity was isolated
from a human hippocampal cDNA library by virtue of the high degree of structural homology …
from a human hippocampal cDNA library by virtue of the high degree of structural homology …
Mutation of an arginine residue in the human glycine receptor transforms β-alanine and taurine from agonists into competitive antagonists
Agonist binding to the inhibitory glycine receptor (GlyR) initiates the opening of a chloride-selective
channel that modulates the neuronal membrane potential. Point mutations of the …
channel that modulates the neuronal membrane potential. Point mutations of the …
Cation-selective mutations in the M2 domain of the inhibitory glycine receptor channel reveal determinants of ion-charge selectivity
Ligand-gated ion channel receptors mediate neuronal inhibition or excitation depending on
their ion charge selectivity. An investigation into the determinants of ion charge selectivity of …
their ion charge selectivity. An investigation into the determinants of ion charge selectivity of …
Startle disease mutations reduce the agonist sensitivity of the human inhibitory glycine receptor.
The receptor for the inhibitory neurotransmitter glycine is a member of the ligand-gated ion
channel receptor superfamily. Point mutations in the gene encoding the alpha 1 subunit of the …
channel receptor superfamily. Point mutations in the gene encoding the alpha 1 subunit of the …
[HTML][HTML] An examination of multiple classes of rare variants in extended families with bipolar disorder
…, AD Shaw, RJN Allcock, A Heath, KD Pierce… - Translational …, 2018 - nature.com
Bipolar disorder (BD) is a complex psychiatric condition with high heritability, the genetic
architecture of which likely comprises both common variants of small effect and rare variants of …
architecture of which likely comprises both common variants of small effect and rare variants of …
[HTML][HTML] Comprehensive cross-disorder analyses of CNTNAP2 suggest it is unlikely to be a primary risk gene for psychiatric disorders
The contactin-associated protein-like 2 (CNTNAP2) gene is a member of the neurexin
superfamily. CNTNAP2 was first implicated in the cortical dysplasia-focal epilepsy (CDFE) …
superfamily. CNTNAP2 was first implicated in the cortical dysplasia-focal epilepsy (CDFE) …