The mental prosthesis: assessing the speed of a P300-based brain-computer interface

E Donchin, KM Spencer… - IEEE transactions on …, 2000 - ieeexplore.ieee.org
Describes a study designed to assess a brain-computer interface (BCI), originally described
by Farwell and Donchin in 1988. The system utilizes the fact that the rare events in the …

Abnormal neural synchrony in schizophrenia

KM Spencer, PG Nestor, MA Niznikiewicz… - Journal of …, 2003 - Soc Neuroscience
Schizophrenia has been conceptualized as a failure of cognitive integration, and abnormalities
in neural circuitry (particularly inhibitory interneurons) have been proposed as a basis for …

Neural synchrony indexes disordered perception and cognition in schizophrenia

KM Spencer, PG Nestor, R Perlmutter… - Proceedings of the …, 2004 - National Acad Sciences
Current views of schizophrenia suggest that it results from abnormalities in neural circuitry,
but empirical evidence in the millisecond range of neural activity has been difficult to obtain. …

Surface-enhanced Raman detection of 2, 4-dinitrotoluene impurity vapor as a marker to locate landmines

JM Sylvia, JA Janni, JD Klein, KM Spencer - Analytical chemistry, 2000 - ACS Publications
Time, cost, and casualties associated with demining efforts underscore the need for improved
detection techniques. Reduction in the number of false positives by directly detecting the …

Spatiotemporal analysis of the late ERP responses to deviant stimuli

KM Spencer, J Dien, E Donchin - Psychophysiology, 2001 - cambridge.org
We used a novel application of principal components analysis (spatiotemporal PCA) to
decompose the event-related brain potentials (ERPs) obtained with a dense electrode array, with …

Neurophysiological biomarkers for drug development in schizophrenia

DC Javitt, KM Spencer, GK Thaker, G Winterer… - Nature Reviews Drug …, 2008 - nature.com
Schizophrenia represents a pervasive deficit in brain function, leading to hallucinations and
delusions, social withdrawal and a decline in cognitive performance. As the underlying …

Parsing the late positive complex: mental chronometry and the ERP components that inhabit the neighborhood of the P300

J Dien, KM Spencer, E Donchin - Psychophysiology, 2004 - Wiley Online Library
Falkenstein, Hohnsbein, and Hoorman (1994) suggested that common measures of P300
latency confound a “P‐SR” component whose latency corresponds to stimulus evaluation time …

γ-Band auditory steady-state responses are impaired in first episode psychosis

KM Spencer, DF Salisbury, ME Shenton… - Biological …, 2008 - Elsevier
BACKGROUND: In chronic schizophrenia and chronic bipolar disorder, γ band (30–100 Hz)
auditory steady-state electroencephalogram responses (ASSRs) are reduced in power and …

A componential analysis of the ERP elicited by novel events using a dense electrode array

KM Spencer, J Dien, E Donchin - Psychophysiology, 1999 - cambridge.org
In this study, we examined the relationship between the novelty P3 and the P300 components
of the brain event-related potential (ERP). Fifteen subjects responded manually to the rare …

Localization of the event-related potential novelty response as defined by principal components analysis

J Dien, KM Spencer, E Donchin - Cognitive Brain Research, 2003 - Elsevier
Recent research indicates that novel stimuli elicit at least two distinct components, the Novelty
P3 and the P300. The P300 is thought to be elicited when a context updating mechanism …