User profiles for Kevin McGregor

Kevin McGregor

Assistant Professor, York University
Verified email at yorku.ca
Cited by 340

[HTML][HTML] An evaluation of methods correcting for cell-type heterogeneity in DNA methylation studies

K McGregor, S Bernatsky, I Colmegna, M Hudson… - Genome biology, 2016 - Springer
Background Many different methods exist to adjust for variability in cell-type mixture proportions
when analyzing DNA methylation studies. Here we present the result of an extensive …

Integrated DNA and fingerprint analyses in the identification of 60‐year‐old mummified human remains discovered in an Alaskan glacier

OM Loreille, RL Parr, KA McGregor… - Journal of forensic …, 2010 - Wiley Online Library
This report describes the identification of a merchant mariner who perished in 1948 when
Northwest Airlines Flight 4422, a DC‐4 carrying 24 seamen and six crew members crashed …

A longitudinal, epigenome-wide study of DNA methylation in anorexia nervosa: results in actively ill, partially weight-restored, long-term remitted and non-eating …

H Steiger, L Booij, E Kahan, K McGregor, L Thaler… - Journal of Psychiatry and …, 2019 - jpn.ca
Background: This study explored state-related tendencies in DNA methylation in people with
anorexia nervosa. Methods: We measured genome-wide DNA methylation in 75 women …

MDiNE: a model to estimate differential co-occurrence networks in microbiome studies

K McGregor, A Labbe, CMT Greenwood - Bioinformatics, 2020 - academic.oup.com
Motivation The human microbiota is the collection of microorganisms colonizing the human
body, and plays an integral part in human health. A growing trend in microbiome analysis is …

[HTML][HTML] Inactivation of interferon regulatory factor 1 causes susceptibility to colitis-associated colorectal cancer

…, L Van Der Kraak, C Meunier, R Cayrol, K McGregor… - Scientific reports, 2019 - nature.com
The mechanisms linking chronic inflammation of the gut (IBD) and increased colorectal
cancer susceptibility are poorly understood. IBD risk is influenced by genetic factors, including …

Photoeffects in Fe2O3 sintered semiconductors

KG McGregor, M Calvin, JW Otvos - Journal of Applied Physics, 1979 - pubs.aip.org
Polycrystalline sintered pellets of α‐Fe 2 O 3 have been studied by capacitance and
photoelectrochemical techniques. The pellets exhibit (i) photocurrent saturation at a given …

Carcinoembryonic Antigen Cell Adhesion Molecule 1 long isoform modulates malignancy of poorly differentiated colon cancer cells

…, S Yumeen, C Turbide, M Saleh, K McGregor… - Gut, 2016 - gut.bmj.com
Objective Nearly 20%–29% of patients with colorectal cancer (CRC) succumb to liver or lung
metastasis and there is a dire need for novel targets to improve the survival of patients with …

Should you pick the PICC? Prolonged use of peripherally inserted central venous catheters in children with intestinal failure

K LaRusso, G Schaack, T Fung, K McGregor… - Journal of Pediatric …, 2019 - Elsevier
Purpose Prolonged central vascular access is a source of significant morbidity in children
with intestinal failure (IF). In an effort to decrease morbidity, our multidisciplinary IF team has …

Methylation of the OXTR gene in women with anorexia nervosa: Relationship to social behavior

…, L Booij, E Kahan, K McGregor… - European Eating …, 2020 - Wiley Online Library
DNA methylation allows for the environmental regulation of gene expression and is believed
to link environmental stressors to psychiatric disorder phenotypes, such as anorexia …

A Bayesian factor analysis model for high-dimensional microbiome count data

…, H Armstrong, S Muthukumarana, K McGregor - arXiv preprint arXiv …, 2024 - arxiv.org
Dimension reduction techniques are among the most essential analytical tools in the
analysis of high-dimensional data. Generalized principal component analysis (PCA) is an …