Functional neural circuit formation during postnatal development involves the elimination of
early-formed redundant synapses. In the neonatal mouse cerebellum, each Purkinje cell is …

Neural circuits in neonatal animals contain numerous redundant synapses that are functionally
immature. During the postnatal period, unnecessary synapses are eliminated while …

Cerebellar climbing fiber (CF) to Purkinje cell (PC) synapses in rodents provides a good
model to study mechanisms underlying postnatal development of synaptic functions and …

Nitric oxide (NO) regulates production of vascular endothelial growth factor (VEGF) by normal
and transformed cells. We demonstrate that NO donors may up-regulate the activity of the …

We report a type of synaptic modulation that involves retrograde signaling from postsynaptic
metabotropic glutamate receptors (mGluRs) to presynaptic cannabinoid receptors. …

During cerebellar development, the main portion of the cerebellar plate neuroepithelium gives
birth to Purkinje cells and interneurons, whereas the rhombic lip, the germinal zone at its …

Endocannabinoids are released from postsynaptic neurons and cause retrograde suppression
of synaptic transmission. Anandamide and 2-arachidonoylglycerol (2-AG) are regarded …

To study the function of GLAST, a glutamate transporter highly expressed in the cerebellar
Bergmann astrocytes, the mouse GLAST gene was inactivated. GLAST‐deficient mice …

Targeted deletion of metabotropic glutamate receptor–subtype 1 (mGluR1) gene can cause
defects in development and function in the cerebellum. We introduced the mGluR1α …

We studied how physiological properties of cerebellar climbing fiber (CF) to Purkinje cell (PC)
synapses change during developmental transition from multiple to mono CF innervation …