[HTML][HTML] Focus: the aging brain: the significance of the default mode network (DMN) in neurological and neuropsychiatric disorders: a review

…, S Hwang, KAB Lapidus - The Yale journal of …, 2016 - ncbi.nlm.nih.gov
The relationship of cortical structure and specific neuronal circuitry to global brain function,
particularly its perturbations related to the development and progression of neuropathology, …

Obsessive-compulsive disorder

WK Goodman, DE Grice, KAB Lapidus… - Psychiatric …, 2014 - psych.theclinics.com
Obsessive-compulsive disorder (OCD) is a common, typically chronic disorder marked by
intrusive and disturbing thoughts (obsessions) and repetitive behaviors (compulsions) that the …

Novel glutamatergic drugs for the treatment of mood disorders

KAB Lapidus, L Soleimani… - … disease and treatment, 2013 - Taylor & Francis
Mood disorders are common and debilitating, resulting in a significant public health burden.
Current treatments are only partly effective and patients who have failed to respond to trials …

A randomized controlled trial of intranasal ketamine in major depressive disorder

KAB Lapidus, CF Levitch, AM Perez, JW Brallier… - Biological …, 2014 - Elsevier
… Author links open overlay panel Kyle AB Lapidus a b , Cara F. Levitch a , Andrew M. Perez
c , Jess W. … KA Lapidus, L. Soleimani, JW Murrough … Lapidus, C. Clark, N. Jarun, B. …

Efficacy of intravenous ketamine for treatment of chronic posttraumatic stress disorder: a randomized clinical trial

…, K Kirkwood, M Aan Het Rot, KAB Lapidus… - JAMA …, 2014 - jamanetwork.com
Importance Few pharmacotherapies have demonstrated sufficient efficacy in the treatment
of posttraumatic stress disorder (PTSD), a chronic and disabling condition. Objective To test …

Elevated prefrontal cortex GABA in patients with major depressive disorder after TMS treatment measured with proton magnetic resonance spectroscopy

…, X Mao, S Banerjee, Z Goodman, KAB Lapidus… - Journal of Psychiatry and …, 2016 - jpn.ca
Background: GABAergic and glutamatergic neurotransmitter systems are central to the
pathophysiology of depression and are potential targets of repetitive transcranial magnetic …

[HTML][HTML] Increased metabolic activity in the septum and habenula during stress is linked to subsequent expression of learned helplessness behavior

MM Mirrione, D Schulz, KAB Lapidus… - Frontiers in human …, 2014 - frontiersin.org
Uncontrollable stress can have a profound effect on an organism's ability to respond
effectively to future stressful situations. Behavior subsequent to uncontrollable stress can vary …

In vivo 1H MRS study of potential associations between glutathione, oxidative stress and anhedonia in major depressive disorder

KAB Lapidus, V Gabbay, X Mao, A Johnson… - Neuroscience …, 2014 - Elsevier
Inflammation and oxidative stress are important mechanisms that have been implicated in
the pathophysiology of major depressive disorder (MDD). Glutathione (GSH) is the most …

History of psychosurgery: a psychiatrist's perspective

KAB Lapidus, BH Kopell, S Ben-Haim, AR Rezai… - World Neurosurgery, 2013 - Elsevier
Interest in using neuromodulation to treat psychiatric disorders is rapidly increasing. The
development of novel tools and techniques, such as deep brain stimulation (DBS), increases …

Diagnosis and treatment of major depressive disorder

L Soleimani, KAB Lapidus… - Neurologic …, 2011 - neurologic.theclinics.com
Major depressive disorder (MDD) encompasses a large number of psychobiological
syndromes with the core features of depressed mood and/or loss of interest associated with …