Neuroendocrine pharmacology of stress
GA Carrasco, LD Van de Kar - European journal of pharmacology, 2003 - Elsevier
Exposure to hostile conditions initiates responses organized to enhance the probability of
survival. These coordinated responses, known as stress responses, are composed of …
survival. These coordinated responses, known as stress responses, are composed of …
Forebrain pathways mediating stress-induced hormone secretion
LD Van de Kar, ML Blair - Frontiers in neuroendocrinology, 1999 - Elsevier
Exposure to hostile conditions initiates the secretion of several hormones, including
corticosterone/cortisol, catecholamines, prolactin, oxytocin, and renin, as part of the survival …
corticosterone/cortisol, catecholamines, prolactin, oxytocin, and renin, as part of the survival …
Serotonin and the neuroendocrine regulation of the hypothalamic-pituitary-adrenal axis in health and disease
NRS Hanley, LD Van de Kar - Vitamins and hormones, 2003 - books.google.com
… Lesions in the central nucleus of the amygdala inhibit the HPA axis response to conditioned
fear stress (Van de Kar et al., 1991a; Campeau and Davis, 1995b; Van de Kar and Blair, …
fear stress (Van de Kar et al., 1991a; Campeau and Davis, 1995b; Van de Kar and Blair, …
5-HT2A receptors stimulate ACTH, corticosterone, oxytocin, renin, and prolactin release and activate hypothalamic CRF and oxytocin-expressing cells
LD Van de Kar, A Javed, Y Zhang, F Serres… - Journal of …, 2001 - Soc Neuroscience
The 5-HT 2A/2C agonist (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane HCl (DOI)
stimulates hypothalamic neurons to increase the secretion of several hormones. This study …
stimulates hypothalamic neurons to increase the secretion of several hormones. This study …
Amygdaloid lesions: differential effect on conditioned stress and immobilization-induced increases in corticosterone and renin secretion
LD Van de Kar, RA Piechowski, PA Rittenhouse… - …, 1991 - karger.com
The purpose of this study was to examine the contribution of the central nucleus of the
amygdala to the expression of stress-induced increase in corticosterone and renin secretion. …
amygdala to the expression of stress-induced increase in corticosterone and renin secretion. …
Cerebrospinal fluid oxytocin, life history of aggression, and personality disorder
BACKGROUND: Data from animal studies have identified oxytocin as an important
modulator of social aggression. We have previously reported on a relationship between …
modulator of social aggression. We have previously reported on a relationship between …
Chronic mild stress induces behavioral and physiological changes, and may alter serotonin 1A receptor function, in male and cycling female rats
…, Z Chen, F Garcia, NA Muma, LD Van de Kar - …, 2005 - Springer
… Van de Kar. The authors are grateful for his guidance and friendship, and he is greatly
missed. This research was supported by United States Public Health Service grants NS34154 …
missed. This research was supported by United States Public Health Service grants NS34154 …
Differential serotonergic innervation of individual hypothalamic nuclei and other forebrain regions by the dorsal and median midbrain raphe nuclei
LD Van de Kar, SA Lorens - Brain research, 1979 - Elsevier
Lesions in the midbrain median but not in the dorsal raphe nucleus significantly decreased
the serotonin (5-HT) content of the hippocampus (61%), medial preoptic area (49%), …
the serotonin (5-HT) content of the hippocampus (61%), medial preoptic area (49%), …
Reduction of 5-hydroxytryptamine (5-HT) 1A-mediated temperature and neuroendocrine responses and 5-HT1A binding sites in 5-HT transporter knockout mice
Q Li, C Wichems, A Heils, LD Van de Kar… - … of Pharmacology and …, 1999 - ASPET
The aim of the present study was to determine whether alterations in 5-hydroxytryptamine (5-HT)
1A receptors would be found in knockout mice lacking the serotonin transporter (5-HTT)…
1A receptors would be found in knockout mice lacking the serotonin transporter (5-HTT)…
[PDF][PDF] Chronic fluoxetine induces a gradual desensitization of 5-HT1A receptors: reductions in hypothalamic and midbrain Gi and G (o) proteins and in …
The time course of fluoxetine-induced desensitization of hypo-thalamic 5-hydroxytryptamine1
receptors was examined in rats. Daily injections of fluoxetine(10 mg/kg/day) for 0, 3, 7, 14 …
receptors was examined in rats. Daily injections of fluoxetine(10 mg/kg/day) for 0, 3, 7, 14 …
