Learning and memory in monozygotic twins discordant for schizophrenia
…, EF Torrey, JM Gold, JD Ragland, LB Bigelow… - Psychological …, 1993 - cambridge.org
… symptoms were assessed by determining the presence or absence of thought disorder,
delusions, or hallucinations at or around the time of the diagnostic interview by two raters (LB …
delusions, or hallucinations at or around the time of the diagnostic interview by two raters (LB …
Cognitive impairments in patients with schizophrenia displaying preserved and compromised intellect
…, TE Goldberg, JM Gold, LB Bigelow… - Archives of general …, 2000 - jamanetwork.com
Background Although intellectual and neurocognitive deficits accompany schizophrenia,
there are inconsistencies in the literature concerning issues of intellectual decline, premorbid …
there are inconsistencies in the literature concerning issues of intellectual decline, premorbid …
Neuropsychological assessment of monozygotic twins discordant for schizophrenia
…, EF Torrey, JM Gold, LB Bigelow… - Archives of general …, 1990 - jamanetwork.com
• A comparison of monozygotic twins discordant for schizophrenia controls for genetic
variance and reduces variance due to environmental circumstances, thus serving to highlight …
variance and reduces variance due to environmental circumstances, thus serving to highlight …
Expression of GABA signaling molecules KCC2, NKCC1, and GAD1 in cortical development and schizophrenia
…, C Colantuoni, MM Herman, LB Bigelow… - Journal of …, 2011 - Soc Neuroscience
GABA signaling molecules are critical for both human brain development and the
pathophysiology of schizophrenia. We examined the expression of transcripts derived from three …
pathophysiology of schizophrenia. We examined the expression of transcripts derived from three …
Cerebral structural pathology in schizophrenia: evidence for a selective prefrontal cortical defect.
…, AR Doran, D Pickar, LB Bigelow… - The American journal …, 1988 - europepmc.org
To replicate earlier findings of central and cortical cerebral structural abnormalities and to
further examine specific prefrontal cortical irregularities in schizophrenia, the authors …
further examine specific prefrontal cortical irregularities in schizophrenia, the authors …
The effect of amphetamine on regional cerebral blood flow during cognitive activation in schizophrenia
…, R Coppola, S Handel, LB Bigelow… - Journal of …, 1991 - Soc Neuroscience
To explore the role of monoamines on cerebral function during specific prefrontal cognitive
activation, we conducted a double-blind placebo- controlled crossover study of the effects of …
activation, we conducted a double-blind placebo- controlled crossover study of the effects of …
Genetic risk of neuropsychological impairment in schizophrenia: a study of monozygotic twins discordant and concordant for the disorder
TE Goldberg, EF Torrey, JM Gold, LB Bigelow… - Schizophrenia …, 1995 - Elsevier
We used a paradigm involving monozygotic (MZ) twin pairs discordant for schizophrenia (n=20)
and concordant for schizophrenia (n=8), as well as normal MZ twin pairs (n=7) in order …
and concordant for schizophrenia (n=8), as well as normal MZ twin pairs (n=7) in order …
Is there cognitive decline in schizophrenia?: A cross-sectional study
…, S Nawroz, TE Goldberg, LB Bigelow… - The British Journal of …, 1994 - cambridge.org
The issue of progressive cognitive decline in patients with schizophrenia has been debated.
We performed a cross-sectional study of patients with chronic schizophrenia, aged from 18 …
We performed a cross-sectional study of patients with chronic schizophrenia, aged from 18 …
Cerebral ventricular enlargement in chronic schizophrenia: An association with poor response to treatment
DR Weinberger, LB Bigelow, JE Kleinman… - Archives of General …, 1980 - jamanetwork.com
• Response to neuroleptic drug treatment in ten chronic schizophrenic patients with enlarged
cerebral ventricles was compared with ten similar patients with normal ventricles. The …
cerebral ventricles was compared with ten similar patients with normal ventricles. The …
Relative risk of attention deficits in siblings of patients with schizophrenia
…, T Gscheidle, M Weirich, LB Bigelow… - American Journal of …, 2000 - Am Psychiatric Assoc
OBJECTIVE: Impaired attention has frequently been observed in studies of unaffected siblings
of patients with schizophrenia. To assess the suitability of impaired attention for use as an …
of patients with schizophrenia. To assess the suitability of impaired attention for use as an …