Although considerable progress has been made in characterising the 5-HT 1A receptor using
agonists, partial agonists or non-selective antagonists, further studies of 5-HT 1A receptor …

Among psychiatric disorders, depression and generalized anxiety are probably the most
common stress-related illnesses. These diseases are underlain, at least partly, by dysfunctions …

Among the seven classes of serotonin (5-hydroxytryptamine, 5-HT) receptorswhich have
been identified to date, the 5-HT1 class is comprised of five receptor types,with the 5-HT1A, 5-…

In order to map the recently cloned serotonin 5-HT 6 receptor in the rat brain and spinal cord,
polyclonal antibodies were raised against a synthetic octadecapeptide corresponding to a …

Psychological distress has long been suspected to influence cancer incidence and mortality.
It remains largely unknown whether and how stress affects the efficacy of anticancer …

Depression is a major health problem with a high prevalence and a heavy socioeconomic
burden in western societies. It is associated with atrophy and impaired functioning of cortico-…

Quantification of receptor binding sites and their encoding mRNAs, and electrophysiological
recordings, were used to assess central serotonin (5-HT) neurotransmission in rats 24 h …

The monoamine hypothesis of depression has dominated our understanding of both the
pathophysiology of depression and the action of pharmacological treatments for the last …

Electrophysiological and autoradiographic approaches were used to assess possible changes
in 5-hydroxytryptamine (serotonin) 5-HT 1A receptors in the rat dorsal raphe nucleus after …

Among the recently cloned serotonin (5-hydroxytryptamine, 5-HT) receptors, the 5-HT 6
subtype is of special interest for at least two reasons: 1) it is abundant in limbic areas which …